The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain
The lysine acetyltransferase KAT6A (MOZ, MYST3) belongs to the MYST family of chromatin regulators, facilitating histone acetylation. Dysregulation of KAT6A has been implicated in developmental syndromes and the onset of acute myeloid leukemia (AML). Previous work suggests that KAT6A is recruited to...
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Philipps-Universität Marburg
2023
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