The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain

The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain

The lysine acetyltransferase KAT6A (MOZ, MYST3) belongs to the MYST family of chromatin regulators, facilitating histone acetylation. Dysregulation of KAT6A has been implicated in developmental syndromes and the onset of acute myeloid leukemia (AML). Previous work suggests that KAT6A is recruited to...

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Autores principales: Weber, Lisa Marie, Jia, Yulin, Stielow, Bastian, Gisselbrecht, Stephen S., Cao, Yinghua, Ren, Yanpeng, Rohner, Iris, King, Jessica, Rothman, Elisabeth, Fischer, Sabrina, Simon, Clara, Forné, Ignasi, Nist, Andrea, Stiewe, Thorsten, Bulyk, Martha L., Wang, Zhanxin, Liefke, Robert
Formato: Artículo
Lenguaje:inglés
Publicado: Philipps-Universität Marburg 2023
Materias:
Medizin
Medical sciences Medicine
Acceso en línea:Texto Completo PDF
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