Arachidonic acid, a clinically adverse mediator in the ovarian cancer microenvironment, impairs JAK‐STAT signaling in macrophages by perturbing lipid raft structures

Arachidonic acid, a clinically adverse mediator in the ovarian cancer microenvironment, impairs JAK‐STAT signaling in macrophages by perturbing lipid raft structures

Survival of ovarian carcinoma is associated with the abundance of immunosuppressed CD163highCD206high tumor‐associated macrophages (TAMs) and high levels of arachidonic acid (AA) in the tumor microenvironment. Here, we show that both associations are functionally linked. Transcriptional profiling re...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Hammoud, Mohamad K., Dietze, Raimund, Pesek, Jelena, Finkernagel, Florian, Unger, Annika, Bieringer, Tim, Nist, Andrea, Stiewe, Thorsten, Bhagwat, Aditya M., Nockher, Wolfgang Andreas, Reinartz, Silke, Müller-Brüsselbach, Sabine, Graumann, Johannes, Müller, Rolf
Формат: Статья
Язык:английский
Опубликовано: Philipps-Universität Marburg 2022
Предметы:
interferon
Medizin
arachidonic acid
ovarian cancer microenvironment
macrophage
STAT
lipid rafts
Medical sciences Medicine
Online-ссылка:PDF-полный текст
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!
No references were found for this record.

Схожие документы