Screening for eukaryotic motifs in Legionella pneumophila reveals Smh1 as bacterial deacetylase of host histones

Screening for eukaryotic motifs in Legionella pneumophila reveals Smh1 as bacterial deacetylase of host histones

Legionella pneumophila (L.p.) is a bacterial pathogen which is a common causative agent of pneumonia. In humans, it infects alveolar macrophages and transfers hundreds of virulence factors that interfere with cellular signalling pathways and the transcriptomic landscape to sustain its own replicatio...

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Auteurs principaux: Herbel, Stefanie M., Moyon, Lambert, Christ, Marvin, Elsayed, Eslam M., Caffrey, Brian E., Malmsheimer, Silke, Grin, Iwan, Hoffmann, Kerstin, Surmann, Kristin, Blankenburg, Sascha, Jung, Anna Lena, Herkt, Christina E., Borsò, Marco, Bozdag, Beyza, Imhof, Axel, Becker, Anke, Wagner, Samuel, Bange, Gert, Völker, Uwe, Bertrams, Wilhelm, Marsico, Annalisa, Schmeck, Bernd
Format: Article
Langue:anglais
Publié: Philipps-Universität Marburg 2022
Sujets:
macrophage
Smh1
histone-deacetylase
Legionella pneumophila
Medizin
Infection
Medical sciences Medicine
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Cote: urn:nbn:de:hebis:04-es2023-01555
Date de publication: 2023-10-04
Source: Erstveröffentlichung: Stefanie M. Herbel, Lambert Moyon, Marvin Christ, Eslam M. Elsayed, Brian E. Caffrey, Silke Malmsheimer, Iwan Grin, Kerstin Hoffmann, Kristin Surmann, Sascha Blankenburg, Anna Lena Jung, Christina E. Herkt, Marco Borsò, Beyza Bozdag, Axel Imhof, Anke Becker, Samuel Wagner, Gert Bange, Uwe Völker, Wilhelm Bertrams, Annalisa Marsico & Bernd Schmeck (2022) Screening for eukaryotic motifs in Legionella pneumophila reveals Smh1 as bacterial deacetylase of host histones, Virulence, 13:1, 2042-2058, DOI: 10.1080/21505594.2022.2149973
Downloads: 14 (2024), 9 (2023)
Lizenz: https://creativecommons.org/licenses/by/4.0
URL d'accès: https://archiv.ub.uni-marburg.de/es/2023/0155
https://doi.org/10.1080/21505594.2022.2149973

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