The pocketome of G-protein-coupled receptors reveals previously untargeted allosteric sites
G-protein-coupled receptors do not only feature the orthosteric pockets, where most endogenous agonists bind, but also a multitude of other allosteric pockets that have come into the focus as potential binding sites for synthetic modulators. Here, to better characterise such pockets, we investigate...
Shranjeno v:
Autoren: | , , , , , , , |
---|---|
Format: | Artikel |
Jezik: | angleščina |
Izdano: |
Philipps-Universität Marburg
2022
|
Teme: | |
Online dostop: | PDF-Volltext |
Oznake: |
Označite
Brez oznak, prvi označite!
|
Publikationen im Open Access gefördert durch die UB