The pocketome of G-protein-coupled receptors reveals previously untargeted allosteric sites

G-protein-coupled receptors do not only feature the orthosteric pockets, where most endogenous agonists bind, but also a multitude of other allosteric pockets that have come into the focus as potential binding sites for synthetic modulators. Here, to better characterise such pockets, we investigate...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Autoren: Hedderich, Janik B., Persechino, Margherita, Becker, Katharina, Heydenreich, Franziska M., Gutermuth, Torben, Bouvier, Michel, Bünemann, Moritz, Kolb, Peter
Format: Artikel
Jezik:angleščina
Izdano: Philipps-Universität Marburg 2022
Teme:
Online dostop:PDF-Volltext
Oznake: Označite
Brez oznak, prvi označite!
Publikationen im Open Access gefördert durch die UB