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The pocketome of G-protein-coupled receptors reveals previously untargeted allosteric sites
G-protein-coupled receptors do not only feature the orthosteric pockets, where most endogenous agonists bind, but also a multitude of other allosteric pockets that have come into the focus as potential binding sites for synthetic modulators. Here, to better characterise such pockets, we investigate...
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| Principais autores: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | inglês |
| Publicado em: |
Philipps-Universität Marburg
2022
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| Assuntos: | |
| Acesso em linha: | Texto Completo em Formato PDF |
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Publikationen im Open Access gefördert durch die UB