Partial p53 reactivation is sufficient to induce cancer regression

Klimovich, Boris; Meyer, Laura; Merle, Nastasja; Neumann, Michelle; König, Alexander M.; Ananikidis, Nikolaos; Keber, Corinna U.; Elmshäuser, Sabrina; Tomofeev, Oleg; Stiewe, Thorsten

Partial p53 reactivation is sufficient to induce cancer regression

Impaired p53 function is one of the central molecular features of a tumor cell and even a partial reduction in p53 activity can increase the cancer risk in mice and men. From a therapeutic perspective it is noteworthy that tumor cells often become addicted to the absence of p53 providing a rationale...

詳細記述

保存先:

書誌詳細
主要な著者:	Klimovich, Boris, Meyer, Laura, Merle, Nastasja, Neumann, Michelle, König, Alexander M., Ananikidis, Nikolaos, Keber, Corinna U., Elmshäuser, Sabrina, Tomofeev, Oleg, Stiewe, Thorsten
フォーマット:	論文
言語:	英語
出版事項:	Philipps-Universität Marburg 2022
主題:	p53 Mouse models Medizin Molecular therapy p53 reactivation Lymphoma Leukemia Tumor suppressor gene Medical sciences Medicine
オンライン･アクセス:	PDFフルテキスト
タグ:	タグ追加タグなし, このレコードへの初めてのタグを付けませんか!

Publikationen im Open Access gefördert durch die UB

Partial p53 reactivation is sufficient to induce cancer regression

類似資料