Partial p53 reactivation is sufficient to induce cancer regression
Impaired p53 function is one of the central molecular features of a tumor cell and even a partial reduction in p53 activity can increase the cancer risk in mice and men. From a therapeutic perspective it is noteworthy that tumor cells often become addicted to the absence of p53 providing a rationale...
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Philipps-Universität Marburg
2022
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