Enhanced firing of locus coeruleus neurons and SK channel dysfunction are conserved in distinct models of prodromal Parkinson’s disease

Matschke, Lina A.; Komadowski, Marlene A.; Stöhr, Annette; Lee, Bolam; Henrich, Martin T.; Griesbach, Markus; Rinné, Susanne; Geibl, Fanni F.; Chiu, Wei-Hua; Koprich, James B.; Brotchie, Jonathan M.; Kiper, Aytug K.; Dolga, Amalia M.; Oertel, Wolfgang H.; Decher, Niels

Enhanced firing of locus coeruleus neurons and SK channel dysfunction are conserved in distinct models of prodromal Parkinson’s disease

Parkinson’s disease (PD) is clinically defined by the presence of the cardinal motor symptoms, which are associated with a loss of dopaminergic nigrostriatal neurons in the substantia nigra pars compacta (SNpc). While SNpc neurons serve as the prototypical cell-type to study cellular vulnerability i...

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Hlavní autoři:	Matschke, Lina A., Komadowski, Marlene A., Stöhr, Annette, Lee, Bolam, Henrich, Martin T., Griesbach, Markus, Rinné, Susanne, Geibl, Fanni F., Chiu, Wei-Hua, Koprich, James B., Brotchie, Jonathan M., Kiper, Aytug K., Dolga, Amalia M., Oertel, Wolfgang H., Decher, Niels
Médium:	Článek
Jazyk:	angličtina
Vydáno:	Philipps-Universität Marburg 2022
Témata:	Medizin Medical sciences Medicine
On-line přístup:	Plný text ve formátu PDF
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Enhanced firing of locus coeruleus neurons and SK channel dysfunction are conserved in distinct models of prodromal Parkinson’s disease

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