Timing of Blood Sample Processing Affects the Transcriptomic and Epigenomic Profiles in CD4+ T-cells of Atopic Subjects

Timing of Blood Sample Processing Affects the Transcriptomic and Epigenomic Profiles in CD4+ T-cells of Atopic Subjects

Optimal pre-analytical conditions for blood sample processing and isolation of selected cell populations for subsequent transcriptomic and epigenomic studies are required to obtain robust and reproducible results. This pilot study was conducted to investigate the potential effects of timing of CD4+...

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Auteurs principaux: Alhamdan, Fahd, Laubhahn, Kristina, Happle, Christine, Habener, Anika, Jirmo, Adan C., Thölken, Clemens, Conca, Raffaele, Chung, Ho-Ryun, Hansen, Gesine, Potaczek, Daniel P., Schaub, Bianca, Grychtol, Ruth, Garn, Holger
Format: Article
Langue:anglais
Publié: Philipps-Universität Marburg 2022
Sujets:
transcriptomics
histone modifications
Medizin
epigenetics
CD4+ T-cells
ChIP sequencing
Medical sciences Medicine
Accès en ligne:Texte intégral en PDF
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