The rationale for the treatment of long-Covid symptoms – A cardiologist's view

The rationale for the treatment of long-Covid symptoms – A cardiologist's view

The ongoing coronavirus disease 2019 pandemic left us with thousands of patients suffering from neurological, cardiovascular, and psychiatric disorders named post-acute sequelae of COVID-19 or just long-Covid. In parallel, the vaccination campaigns against SARS-CoV-2 spike protein saved millions of...

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Autores principales: Schieffer, Elisabeth, Schieffer, Bernhard
Formato: Artículo
Lenguaje:inglés
Publicado: Philipps-Universität Marburg 2022
Materias:
lipid – hybrid nanoparticles
Medizin
renin-angiotensin system
kalkrein-kinin system
histamin challenge
HDL - cholesterol
long-Covid syndrome
cholesterol
Medical sciences Medicine
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Sumario:The ongoing coronavirus disease 2019 pandemic left us with thousands of patients suffering from neurological, cardiovascular, and psychiatric disorders named post-acute sequelae of COVID-19 or just long-Covid. In parallel, the vaccination campaigns against SARS-CoV-2 spike protein saved millions of lives worldwide but long-Covid symptoms also appeared rarely following vaccination with a strong overlap to the “canonical” long-Covid symptoms. A therapeutic strategy targeting both, post-VAC and post-SARS-CoV-2 long-Covid symptoms is warranted since exposure to the S-protein either by vaccination or SARS-CoV-2 infection may trigger identical immuno-inflammatory cascades resulting in long-Covid symptoms.
Notas:Gefördert durch den Open-Access-Publikationsfonds der UB Marburg.
Descripción Física:10 Seiten
DOI:10.3389/fcvm.2022.992686

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