Dual PI3K/mTOR Inhibitor NVP-BEZ235 Leads to a Synergistic Enhancement of Cisplatin and Radiation in Both HPV-Negative and -Positive HNSCC Cell Lines
Head and neck cancers (HNSCCs), especially in the advanced stages, are predominantly treated by radiochemotherapy, including cisplatin. The cure rates are clearly higher for HPV-positive HNSCCs when compared to HPV-negative HNSCCs. For both entities, this treatment is accompanied by serious adverse...
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Format: | Artikel |
Sprache: | Englisch |
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Philipps-Universität Marburg
2023
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urn:nbn:de:hebis:04-es2023-00333 |
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Publikationsdatum: |
2023-04-03 |
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Erstveröffentlichung: Subtil, F.S.B.; Gröbner, C.; Recknagel, N.; Parplys, A.C.; Kohl, S.; Arenz, A.; Eberle, F.; Dikomey, E.; Engenhart-Cabillic, R.; Schötz, U. Dual PI3K/mTOR Inhibitor NVP-BEZ235 Leads to a Synergistic Enhancement of Cisplatin and Radiation in Both HPV-Negative and -Positive HNSCC Cell Lines. Cancers 2022, 14, 3160. https://doi.org/10.3390/cancers14133160 |
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43 (2024), 73 (2023) |
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https://creativecommons.org/licenses/by/4.0 |
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https://archiv.ub.uni-marburg.de/es/2023/0033 https://doi.org/10.3390/cancers14133160 |