Co-delivery of carbonic anhydrase IX inhibitor and doxorubicin as a promising approach to address hypoxia-induced chemoresistance

Amin, Muhammad Umair; Ali, Sajid; Alie, Muhammad Yasir; Fuhrmann, Dominik C.; Tarik, Imran; Seitz, Benjamin S.; Preis, Eduard; Büßler, Jana; Brüne, Bernhard; Bakowsky, Udo

Co-delivery of carbonic anhydrase IX inhibitor and doxorubicin as a promising approach to address hypoxia-induced chemoresistance

Hypoxia, an oxygen-deprived condition of the tumor, is one of the major reasons for resistance to chemotherapy. Carbonic anhydrases are generally involved in pH homeostasis in normal conditions, but in solid tumors having a strong relation with hypoxia, the car...

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Bibliographic Details
Main Authors:	Amin, Muhammad Umair, Ali, Sajid, Alie, Muhammad Yasir, Fuhrmann, Dominik C., Tarik, Imran, Seitz, Benjamin S., Preis, Eduard, Büßler, Jana, Brüne, Bernhard, Bakowsky, Udo
Format:	Article
Language:	English
Published:	Philipps-Universität Marburg 2023
Subjects:	Pharmakologie, Therapeutik Hypoxia mesoporous silica nanoparticles liposomes co-delivery CA-IX enzyme inhibition Pharmacology & therapeutics, prescription drugs
Online Access:	PDF Full Text
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Co-delivery of carbonic anhydrase IX inhibitor and doxorubicin as a promising approach to address hypoxia-induced chemoresistance

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