Inflammation and Wasting of Skeletal Muscles in Kras-p53-Mutant Mice with Intraepithelial Neoplasia and Pancreatic Cancer — When Does Cachexia Start?

Hildebrand, Wulf; Keck, Jan; Schmich, Simon; Bonaterra, Gabriel A.; Wilhelm, Beate; Schwarzbach, Hans; Eva, Anna; Bertoune, Mirjam; Slater, Emily P.; Fendrich, Volker; Kinscherf, Ralf

Inflammation and Wasting of Skeletal Muscles in Kras-p53-Mutant Mice with Intraepithelial Neoplasia and Pancreatic Cancer — When Does Cachexia Start?

Skeletal muscle wasting critically impairs the survival and quality of life in patients with pancreatic ductal adenocarcinoma (PDAC). To identify the local factors initiating muscle wasting, we studied inflammation, fiber cross-sectional area (CSA), composition, amino acid metabolism and capillar...

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Autoren:	Hildebrand, Wulf, Keck, Jan, Schmich, Simon, Bonaterra, Gabriel A., Wilhelm, Beate, Schwarzbach, Hans, Eva, Anna, Bertoune, Mirjam, Slater, Emily P., Fendrich, Volker, Kinscherf, Ralf
Formato:	Artigo
Idioma:	inglés
Publicado:	Philipps-Universität Marburg 2023
Schlagworte:	gastrointestinal cancer cancer cachexia muscle atrophy cytokines sarcopenia Medizin weight loss Medical sciences Medicine
Acceso en liña:	Texto completo PDF
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Inflammation and Wasting of Skeletal Muscles in Kras-p53-Mutant Mice with Intraepithelial Neoplasia and Pancreatic Cancer — When Does Cachexia Start?

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