Inflammation and Wasting of Skeletal Muscles in Kras-p53-Mutant Mice with Intraepithelial Neoplasia and Pancreatic Cancer — When Does Cachexia Start?

Inflammation and Wasting of Skeletal Muscles in Kras-p53-Mutant Mice with Intraepithelial Neoplasia and Pancreatic Cancer — When Does Cachexia Start?

Skeletal muscle wasting critically impairs the survival and quality of life in patients with pancreatic ductal adenocarcinoma (PDAC). To identify the local factors initiating muscle wasting, we studied inflammation, fiber cross-sectional area (CSA), composition, amino acid metabolism and capillar...

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Bibliographic Details
Main Authors: Hildebrand, Wulf, Keck, Jan, Schmich, Simon, Bonaterra, Gabriel A., Wilhelm, Beate, Schwarzbach, Hans, Eva, Anna, Bertoune, Mirjam, Slater, Emily P., Fendrich, Volker, Kinscherf, Ralf
Format: Article
Language:English
Published: Philipps-Universität Marburg 2023
Subjects:
gastrointestinal cancer
cancer cachexia
muscle atrophy
cytokines
sarcopenia
Medizin
weight loss
Medical sciences Medicine
Online Access:PDF Full Text
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Publikationen im Open Access gefördert durch die UB

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