Robustness of the Autophagy Pathway to Somatic Copy Number Losses

Robustness of the Autophagy Pathway to Somatic Copy Number Losses

Autophagy allows cells to temporarily tolerate energy stress by replenishing critical metabolites through self-digestion, thereby attenuating the cytotoxic effects of anticancer drugs that target tumor metabolism. Autophagy defects could therefore mark a metabolically vulnerable cancer state and ope...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Polo, Pierfrancesco, Gremke, Niklas, Stiewe, Thorsten, Wanzel, Michael
Materialtyp: Artikel
Språk:engelska
Publicerad: Philipps-Universität Marburg 2023
Ämnen:
aerobic glycolysis
cancer metabolism
somatic copy number alterations (SCNAs)
Medizin
metabolic cancer ther
copy number loss
haploinsufficiency
autophagy
Medical sciences Medicine
Länkar:PDF-fulltext
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!
Publikationen im Open Access gefördert durch die UB

Liknande verk