TLR8 is activated by 5ʹ-methylthioinosine, a Plasmodium falciparum-derived intermediate of the purine salvage pathway

TLR8 is activated by 5ʹ-methylthioinosine, a Plasmodium falciparum-derived intermediate of the purine salvage pathway

The innate immune recognition of the malaria-causing pathogen Plasmodium falciparum (P. falciparum) is not fully explored. Here, we identify the nucleoside 5ʹ-methylthioinosine (MTI), a Plasmodium-specific intermediate of the purine salvage pathway, as a pathogen-derived Toll-like receptor 8 (TLR8)...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Köllisch, Gabriele, Venegas Solis, Francisco, Obermann, Hannah-Lena, Eckert, Jeannine, Bauer, Stefan, Vierbuchen, Tim
Materialtyp: Artikel
Språk:engelska
Publicerad: Philipps-Universität Marburg 2023
Ämnen:
Medizin
Medical sciences Medicine
Länkar:PDF-fulltext
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!
Publikationen im Open Access gefördert durch die UB

Liknande verk