IL1 Pathway in HPV-Negative HNSCC Cells Is an Indicator of Radioresistance After Photon and Carbon Ion Irradiation Without Functional Involvement

IL1 Pathway in HPV-Negative HNSCC Cells Is an Indicator of Radioresistance After Photon and Carbon Ion Irradiation Without Functional Involvement

Treatment of locally advanced HPV-negative head and neck squamous cell carcinoma (HNSCC) with photon radiation is the standard of care but shows only moderate success. Alterations in response toward DNA DSB repair, apoptosis, and senescence are underlying determinants of radioresistance in the tu...

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Bibliografski detalji
Glavni autori: Tiwari, Dinesh Kumar, Hannen, Ricarda, Unger, Kristian, Kohl, Sibylla, Heß, Julia, Lauber, Kirsten, Subtil, Florentine S. B., Dikomey, Ekkehard, Engenhart-Cabillic, Rita, Schötz, Ulrike
Format: Članak
Jezik:engleski
Izdano: Philipps-Universität Marburg 2022
Teme:
Medizin
IL1
SASP
carbon ion
tumor
HNSCC
photon
radioresistance
senescence
Medical sciences Medicine
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