ADAM8-Dependent Extracellular Signaling in the Tumor Microenvironment Involves Regulated Release of Lipocalin 2 and MMP-9

ADAM8-Dependent Extracellular Signaling in the Tumor Microenvironment Involves Regulated Release of Lipocalin 2 and MMP-9

The metalloprotease-disintegrin ADAM8 is critically involved in the progression of pancreatic cancer. Under malignant conditions, ADAM8 is highly expressed and could play an important role in cell–cell communication as expression has been observed in tumor and immune cells of the tumor microenvironm...

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מידע ביבליוגרפי
Autoren: Cook, Lena, Sengelmann, Marie, Winkler, Birte, Nagl, Constanze, Koch, Sarah, Schlomann, Uwe, Slater, Emily P., Miller, Miles A., von Strandmann, Elke Pogge, Dörsam, Bastian, Preußer, Christian, Bartsch, Jörg W.
פורמט: Artikel
שפה:אנגלית
יצא לאור: Philipps-Universität Marburg 2022
נושאים:
ADAM8
lipocalin 2
MMP-9
extracellular vesicles
regulation
tumor microenvironment
Medizin
PDAC
Medical sciences Medicine
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