ADAM8-Dependent Extracellular Signaling in the Tumor Microenvironment Involves Regulated Release of Lipocalin 2 and MMP-9

ADAM8-Dependent Extracellular Signaling in the Tumor Microenvironment Involves Regulated Release of Lipocalin 2 and MMP-9

The metalloprotease-disintegrin ADAM8 is critically involved in the progression of pancreatic cancer. Under malignant conditions, ADAM8 is highly expressed and could play an important role in cell–cell communication as expression has been observed in tumor and immune cells of the tumor microenvironm...

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Detalles Bibliográficos
Autores principales: Cook, Lena, Sengelmann, Marie, Winkler, Birte, Nagl, Constanze, Koch, Sarah, Schlomann, Uwe, Slater, Emily P., Miller, Miles A., von Strandmann, Elke Pogge, Dörsam, Bastian, Preußer, Christian, Bartsch, Jörg W.
Formato: Artículo
Lenguaje:inglés
Publicado: Philipps-Universität Marburg 2022
Materias:
ADAM8
lipocalin 2
MMP-9
extracellular vesicles
regulation
tumor microenvironment
Medizin
PDAC
Medical sciences Medicine
Acceso en línea:Texto Completo PDF
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