ADAM8-Dependent Extracellular Signaling in the Tumor Microenvironment Involves Regulated Release of Lipocalin 2 and MMP-9

ADAM8-Dependent Extracellular Signaling in the Tumor Microenvironment Involves Regulated Release of Lipocalin 2 and MMP-9

The metalloprotease-disintegrin ADAM8 is critically involved in the progression of pancreatic cancer. Under malignant conditions, ADAM8 is highly expressed and could play an important role in cell–cell communication as expression has been observed in tumor and immune cells of the tumor microenvironm...

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Hlavní autoři: Cook, Lena, Sengelmann, Marie, Winkler, Birte, Nagl, Constanze, Koch, Sarah, Schlomann, Uwe, Slater, Emily P., Miller, Miles A., von Strandmann, Elke Pogge, Dörsam, Bastian, Preußer, Christian, Bartsch, Jörg W.
Médium: Článek
Jazyk:angličtina
Vydáno: Philipps-Universität Marburg 2022
Témata:
ADAM8
lipocalin 2
MMP-9
extracellular vesicles
regulation
tumor microenvironment
Medizin
PDAC
Medical sciences Medicine
On-line přístup:Plný text ve formátu PDF
Tagy: Přidat tag
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