PEGylated Chitosan Nanoparticles Encapsulating Ascorbic Acid and Oxaliplatin Exhibit Dramatic Apoptotic Effects against Breast Cancer Cells

PEGylated Chitosan Nanoparticles Encapsulating Ascorbic Acid and Oxaliplatin Exhibit Dramatic Apoptotic Effects against Breast Cancer Cells

: This study aims to design a pH-responsive dual-loaded nanosystem based on PEGylated chitosan nanoparticles loaded with ascorbic acid (AA) and oxaliplatin (OX) for the effective treatment of breast cancer. In this regard, non-PEGylated and PEGylated chitosan nanoparticles (CS NPs) loaded with ei...

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Autori principali: Fahmy, Sherif Ashraf, Ramzy, Asmaa, Mandour, Asmaa A., Nasr, Soad, Abdelnaser, Anwar, Bakowsky, Udo, Azzazy, Hassan Mohamed El-Said
Natura: Articolo
Lingua:inglese
Pubblicazione: Philipps-Universität Marburg 2022
Soggetti:
breast cancer
PEG
Medizin
ionic gelation method
chitosan nanoparticles
ascorbic acid (vitamin C)
oxaliplatin
Medical sciences Medicine
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