PEGylated Chitosan Nanoparticles Encapsulating Ascorbic Acid and Oxaliplatin Exhibit Dramatic Apoptotic Effects against Breast Cancer Cells

PEGylated Chitosan Nanoparticles Encapsulating Ascorbic Acid and Oxaliplatin Exhibit Dramatic Apoptotic Effects against Breast Cancer Cells

: This study aims to design a pH-responsive dual-loaded nanosystem based on PEGylated chitosan nanoparticles loaded with ascorbic acid (AA) and oxaliplatin (OX) for the effective treatment of breast cancer. In this regard, non-PEGylated and PEGylated chitosan nanoparticles (CS NPs) loaded with ei...

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Autors principals: Fahmy, Sherif Ashraf, Ramzy, Asmaa, Mandour, Asmaa A., Nasr, Soad, Abdelnaser, Anwar, Bakowsky, Udo, Azzazy, Hassan Mohamed El-Said
Format: Article
Idioma:anglès
Publicat: Philipps-Universität Marburg 2022
Matèries:
breast cancer
PEG
Medizin
ionic gelation method
chitosan nanoparticles
ascorbic acid (vitamin C)
oxaliplatin
Medical sciences Medicine
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