Canlyniadau Chwilio - Klebe, Gerhard (Prof.Dr.)

17β Hydroxysteroid Dehydrogenase 14 (17β-HSD14): Entwicklung und Synthese potenter und selektiver Inhibitoren zur strukturellen Charakterisierung und Untersuchung der physiologisch... gan Braun, Florian

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Structure-Based Design of a Blood Coagulation Factor XIII Blocker gan Stieler, Martin

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Strukturbasierte Entwicklung und Charakterisierung von Inhibitoren der TGT,ein mögliches Ziel zur Therapie der Bakterienruhr gan Ehrmann, Frederik Rainer

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From Active-Site Mapping to Lead Discovery using Fragment-based Approaches on the Aspartic protease Endothiapepsin gan Radeva, Nedyalka

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Insights into Protein-Ligand Molecular Recognition: Thermodynamic, Kinetic and Structural Characterization of Inhibitor Binding to Aldose Reductase and Carbonic Anhydrase II gan Rechlin, Chris

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Development of models to describe the dynamics and interaction with water molecules in protein-ligand binding gan Betz, Michael

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Strukturelle und thermodynamische Charakterisierung der Fragment und Liganden Bindung an Thrombin gan Rühmann, Eggert Henning

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Methods for the Efficient Comparison of Protein Binding Sites and for the Assessment of Protein-Ligand Complexes gan Krotzky, Timo

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Investigations on lin-Benzopurines With Respect to Dissociation Behavior, Pocket Cross-Talk, Targeting Resistance Mutants, Residual Mobility, and Scaffold Optimization gan Neeb, Manuel

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Nichtkompetitive Inhibition der tRNA-Guanin Transglycosylase durch Störung der essentiellen Protein-Protein-Interaktion gan Jakobi, Stephan

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lin-Benzopurines as Inhibitors of tRNA-Guanine Transglycosylase: Perturbance of Homodimer Formation, Import of Water Clusters and Determinants of Crystallographical Disorder gan Immekus, Florian Peter Philip

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Optimization of Clustering and Database Screening Procedures for Cavbase and Virtual Screening for Novel Antimalarial and Antibacterial Molecules gan Glinca, Serghei

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The Role of Water in Protein-Ligand Binding: A Comprehensive Study by Crystallography and Isothermal Titration Calorimetry gan Biela, Adam

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Strukturbasiertes Wirkstoffdesign am Beispiel der Zielproteine HIV-1 Protease, Transglutaminase 2 und Faktor XIII gan Lindemann, Ina

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Development and Improvement of Tools and Algorithms for the Problem of Atom Type Perception and for the Assessment of Protein-Ligand-Complex Geometries gan Neudert, Gerd

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Knowledge-based Optimization of Protein-Ligand-Complex Geometries gan Spitzmüller, Andreas

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Fragment based Drug Discovery; Design and Validation of a Fragment Library; Computer-based Fragment Screening and Fragment-to-Lead Expansion gan Craan, Tobias Friedrich

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Carbonic Anhydrase II: A Model System for Artificial Copper Center Design, Protein-guided Cycloadditions, Tethering Screenings and Fragment-based Lead Discovery gan Schulze Wischeler, Johannes

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Optimiertes Design kombinatorischer Verbindungsbibliotheken durch Genetische Algorithmen und deren Bewertung anhand wissensbasierter Protein-Ligand Bindungsprofile gan Pfeffer, Patrick

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The well-tempered Thrombin - A systematic crystallographic and calorimetric study on the thermodynamics of serine-protease inhibition gan Baum, Bernhard

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