Resultados da pesquisa - Stiewe, Thorsten

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  1. 1
    Pericentromeric satellite lncRNAs are induced in cancer-associated fibroblasts and regulate their functions in lung tumorigenesis

    Pericentromeric satellite lncRNAs are induced in cancer-associated fibroblasts and regulate their functions in lung tumorigenesis Por Enukashvily, Natella I., Ponomartsev, Nikita V., Ketkar, Avanee, Suezov, Roman, Chubar, Anna V., Prijibelski, Andrey D., Shafranskaya, Daria D., Elmshäuser, Sabrina, Keber, Corinna U., Stefanova, Vera N., Akopov, Andrey L., Klingmüller, Ursula, Stiewe, Thorsten, Lauth, Matthias, Brichkina, Anna I., Pfefferle, Petra I.

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  2. 2
    Monitoring autochthonous lung tumors induced by somatic CRISPR gene editing in mice using a secreted luciferase

    Monitoring autochthonous lung tumors induced by somatic CRISPR gene editing in mice using a secreted luciferase Por Merle, Nastasja, Elmshäuser, Sabrina, Strassheimer, Florian, Wanzel, Michael, König, Alexander M., Funk, Julianne, Neumann, Michelle, Kochhan, Katharina, Helmprobst, Frederik, Pagenstecher, Axel, Nist, Andrea, Mernberg, Marco, Schneider, André, Braun, Thomas, Borggrefe, Tilman, Savai, Rajkumar, Timofeev, Oleg, Stiewe, Thorsten

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  3. 3
    The importin beta superfamily member RanBP17 exhibits a role in cell proliferation and is associated with improved survival of patients with HPV+ HNSCC

    The importin beta superfamily member RanBP17 exhibits a role in cell proliferation and is associated with improved survival of patients with HPV+ HNSCC Por Mandic, Robert, Marquardt, André, Terhorst, Philip, Ali, Uzma, Nowak-Rossmann, Annette, Cai, Chengzhong, Rodepeter, Fiona R., Stiewe, Thorsten, Wezorke, Bernadette, Wanzel, Michael, Neff, Andreas, Stuck, Boris A., Bette, Michael

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  4. 4
    Arachidonic acid, a clinically adverse mediator in the ovarian cancer microenvironment, impairs JAK‐STAT signaling in macrophages by perturbing lipid raft structures

    Arachidonic acid, a clinically adverse mediator in the ovarian cancer microenvironment, impairs JAK‐STAT signaling in macrophages by perturbing lipid raft structures Por Hammoud, Mohamad K., Dietze, Raimund, Pesek, Jelena, Finkernagel, Florian, Unger, Annika, Bieringer, Tim, Nist, Andrea, Stiewe, Thorsten, Bhagwat, Aditya M., Nockher, Wolfgang Andreas, Reinartz, Silke, Müller-Brüsselbach, Sabine, Graumann, Johannes, Müller, Rolf

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  5. 5
    The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain

    The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain Por Weber, Lisa Marie, Jia, Yulin, Stielow, Bastian, Gisselbrecht, Stephen S., Cao, Yinghua, Ren, Yanpeng, Rohner, Iris, King, Jessica, Rothman, Elisabeth, Fischer, Sabrina, Simon, Clara, Forné, Ignasi, Nist, Andrea, Stiewe, Thorsten, Bulyk, Martha L., Wang, Zhanxin, Liefke, Robert

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  6. 6
    Phosphorylierung der p53 H1-Helix: Rolle für Tumorsuppression und Tumorigenese

    Phosphorylierung der p53 H1-Helix: Rolle für Tumorsuppression und Tumorigenese Por Niederau, Edmund Constantin

    Publicado em 2023
    Outros Autores: “...Stiewe, Thorsten (Prof. Dr. med.)...”
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  7. 7
    Partial p53 reactivation is sufficient to induce cancer regression

    Partial p53 reactivation is sufficient to induce cancer regression Por Klimovich, Boris, Meyer, Laura, Merle, Nastasja, Neumann, Michelle, König, Alexander M., Ananikidis, Nikolaos, Keber, Corinna U., Elmshäuser, Sabrina, Tomofeev, Oleg, Stiewe, Thorsten

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  8. 8
    Mutagenese des endogenen TP53-Lokus durch CRISPR/Cas9-vermittelte homologe Rekombination & Base Editing in Lungenkarzinomzellen

    Mutagenese des endogenen TP53-Lokus durch CRISPR/Cas9-vermittelte homologe Rekombination & Base Editing in Lungenkarzinomzellen Por Drangenstein, Daniel

    Publicado em 2023
    Outros Autores: “...Stiewe, Thorsten (Prof. Dr.)...”
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  9. 9
    Advanced preclinical CRISPR mouse models to explore context-dependent effects of TP53 mutations in cancer

    Advanced preclinical CRISPR mouse models to explore context-dependent effects of TP53 mutations in cancer Por Merle, Nastasja

    Publicado em 2023
    Outros Autores: “...Stiewe, Thorsten (Prof. Dr.)...”
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  10. 10
    Robustness of the Autophagy Pathway to Somatic Copy Number Losses

    Robustness of the Autophagy Pathway to Somatic Copy Number Losses Por Polo, Pierfrancesco, Gremke, Niklas, Stiewe, Thorsten, Wanzel, Michael

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  11. 11
    The Nuclear Proteins TP73 and CUL4A Confer Resistance to Cytarabine by Induction of Translesion DNA Synthesis via Mono-ubiquitination of PCNA

    The Nuclear Proteins TP73 and CUL4A Confer Resistance to Cytarabine by Induction of Translesion DNA Synthesis via Mono-ubiquitination of PCNA Por Rehberger, Miriam, Schäfer, Jonas A., Krampitz, Anna-Maria, Bretz, Anne Catherine, Jost, Lukas, Haferlach, Torsten, Stiewe, Thorsten, Neubauer, Andreas

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  12. 12
    Zwischen Zellzyklus-Arrest und Apoptose – p53-Kooperativitätsmutanten in vivo

    Zwischen Zellzyklus-Arrest und Apoptose – p53-Kooperativitätsmutanten in vivo Por Schäfer, Jonas Aaron

    Publicado em 2022
    Outros Autores: “...Stiewe, Thorsten (Prof. Dr.)...”
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  13. 13
    Functional characterization of the TP53 mutome using CRISPR/Cas9 saturating mutagenesis

    Functional characterization of the TP53 mutome using CRISPR/Cas9 saturating mutagenesis Por Klimovich, Mariia

    Publicado em 2021
    Outros Autores: “...Stiewe, Thorsten (Prof. Dr.)...”
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  14. 14
    Die Rolle der DNA-Bindungskooperativität für die p53-vermittelte Tumorsuppression im Lungentumor-Xenograft-Modell

    Die Rolle der DNA-Bindungskooperativität für die p53-vermittelte Tumorsuppression im Lungentumor-Xenograft-Modell Por Brehm, Corinna Ulrike

    Publicado em 2018
    Outros Autores: “...Stiewe, Thorsten (Prof. Dr.)...”
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  15. 15
    Die Interaktion zwischen p53 und p73 als molekulare Zielstruktur in der Tumortherapie

    Die Interaktion zwischen p53 und p73 als molekulare Zielstruktur in der Tumortherapie Por Müller, Maximilian

    Publicado em 2018
    Outros Autores: “...Stiewe, Thorsten (Prof. Dr.)...”
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  16. 16
    Establishment and characterization of preclinical mouse models for evaluation of oncogenic and tumor-suppressive properties of p53 family members

    Establishment and characterization of preclinical mouse models for evaluation of oncogenic and tumor-suppressive properties of p53 family members Por Fuchs, Jeannette

    Publicado em 2016
    Outros Autores: “...Stiewe, Thorsten (Prof. Dr.)...”
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  17. 17
    Genomweite funktionelle Analyse von p53-Bindungsstellen via ChIPseq

    Genomweite funktionelle Analyse von p53-Bindungsstellen via ChIPseq Por Heyl, Charlotte

    Publicado em 2015
    Outros Autores: “...Stiewe, Thorsten (Prof. Dr.)...”
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  18. 18
    Einfluss der DNA-Bindungskooperativität von p53 auf die Tumorsuppressoraktivität & Beobachtung der Entwicklungsdynamik von Tumorklonen in vitro & in vivo mittels sekretierter Luciferasen

    Einfluss der DNA-Bindungskooperativität von p53 auf die Tumorsuppressoraktivität & Beobachtung der Entwicklungsdynamik von Tumorklonen in vitro & in vivo mittels sekretierter Lucif... Por Charles, Joël Pierre Alexandre

    Publicado em 2015
    Outros Autores: “...Stiewe, Thorsten (Prof. Dr.)...”
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  19. 19
    Etablierung eines NSCLC-Modells zur Untersuchung der Rolle der p53 DNA Bindungskooperativität für Zellschicksalsentscheidungen in vitro und in vivo

    Etablierung eines NSCLC-Modells zur Untersuchung der Rolle der p53 DNA Bindungskooperativität für Zellschicksalsentscheidungen in vitro und in vivo Por Kahnis, Robert Walter

    Publicado em 2015
    Outros Autores: “...Stiewe, Thorsten (Prof. Dr.)...”
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