Arama Sonuçları - Klebe, Gerhard (Prof. Dr.)

Sonuçları Daraltın
  1. 1
    Leitstruktursuche mithilfe eines kristallographischen Fragment-Screenings zur Inhibierung des Klasse-II-Chaperons IpgC aus Shigella flexneri

    Leitstruktursuche mithilfe eines kristallographischen Fragment-Screenings zur Inhibierung des Klasse-II-Chaperons IpgC aus Shigella flexneri Yazar: Gárdonyi, Marina

    Baskı/Yayın Bilgisi 2021
    Diğer Yazarlar: “…Klebe, Gerhard (Prof. Dr.)…”
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  2. 2
    Optimization of the Drug Design Process by Ligand Preorganization and Occupancy of Transient Binding Pockets Based on the Model Proteins Thrombin and Aldose Reductase

    Optimization of the Drug Design Process by Ligand Preorganization and Occupancy of Transient Binding Pockets Based on the Model Proteins Thrombin and Aldose Reductase Yazar: Sandner, Anna Sophie

    Baskı/Yayın Bilgisi 2022
    Diğer Yazarlar: “…Klebe, Gerhard (Prof. Dr.)…”
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  3. 3
    Mutational Studies on 17β-HSD14, Serial Synchrotron X-ray Crystallography, Solubility Enhancement using Cyclodextrins and Fragment-Based Drug Discovery Multiple Blocks to Pave the Road of Drug Design

    Mutational Studies on 17β-HSD14, Serial Synchrotron X-ray Crystallography, Solubility Enhancement using Cyclodextrins and Fragment-Based Drug Discovery Multiple Blocks to Pave the... Yazar: Badran, Mohammed

    Baskı/Yayın Bilgisi 2021
    Diğer Yazarlar: “…Klebe, Gerhard (Prof. Dr.)…”
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  4. 4
    Neue Ansätze zur Entwicklung von Modulatoren der homodimeren tRNA-Guanin-Transglycosylase

    Neue Ansätze zur Entwicklung von Modulatoren der homodimeren tRNA-Guanin-Transglycosylase Yazar: Nguyen, Andreas

    Baskı/Yayın Bilgisi 2020
    Diğer Yazarlar: “…Klebe, Gerhard (Prof. Dr.)…”
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  5. 5
    Fragment-basierte Leitstruktursuche am Beispiel der Proteinkinase A

    Fragment-basierte Leitstruktursuche am Beispiel der Proteinkinase A Yazar: Oebbeke, Matthias

    Baskı/Yayın Bilgisi 2021
    Diğer Yazarlar: “…Klebe, Gerhard (Prof. Dr.)…”
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  6. 6
    From Serendipity to the Rational Design of Protein–Protein Interface Modulators Targeting a tRNA-Modifying Enzyme

    From Serendipity to the Rational Design of Protein–Protein Interface Modulators Targeting a tRNA-Modifying Enzyme Yazar: Nguyen, Dzung

    Baskı/Yayın Bilgisi 2020
    Diğer Yazarlar: “…Klebe, Gerhard (Prof. Dr.)…”
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  7. 7
    Thermodynamic, Kinetic and Crystallographic Investigations of Benzenesulfonamides as Ligands of Human Carbonic Anhydrase II

    Thermodynamic, Kinetic and Crystallographic Investigations of Benzenesulfonamides as Ligands of Human Carbonic Anhydrase II Yazar: Glöckner, Steffen

    Baskı/Yayın Bilgisi 2020
    Diğer Yazarlar: “…Klebe, Gerhard Prof. Dr.…”
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  8. 8
    Do All Roads Really Lead to Rome? Learnings from Comparative Analysis using SPR, NMR, & X-Ray Crystallography to Optimize Fragment Screening in Drug Discovery.

    Do All Roads Really Lead to Rome? Learnings from Comparative Analysis using SPR, NMR, & X-Ray Crystallography to Optimize Fragment Screening in Drug Discovery. Yazar: Hassaan, Engi

    Baskı/Yayın Bilgisi 2019
    Diğer Yazarlar: “…Klebe, Gerhard (Prof. Dr.)…”
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  9. 9
    Synthese von D-Phe/D-DiPhe-Pro-basierenden Liganden und deren biophysikalischen Charakterisierung zur Selektivitätsstudie von Thrombin und Trypsin sowie ein synthetischer Beitrag zur Darstellung von Inhibitoren der Aldose-Reduktase und Carboanhydrase II

    Synthese von D-Phe/D-DiPhe-Pro-basierenden Liganden und deren biophysikalischen Charakterisierung zur Selektivitätsstudie von Thrombin und Trypsin sowie ein synthetischer Beitrag z... Yazar: Ngo, Trong Khang

    Baskı/Yayın Bilgisi 2020
    Diğer Yazarlar: “…Klebe, Gerhard (Prof. Dr.)…”
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  10. 10
    Targeting farnesyl pyrophosphate synthase of Trypanosoma cruzi by fragment-based lead discovery

    Targeting farnesyl pyrophosphate synthase of Trypanosoma cruzi by fragment-based lead discovery Yazar: Petrick, Joy Kristin

    Baskı/Yayın Bilgisi 2019
    Diğer Yazarlar: “…Klebe, Gerhard (Prof. Dr.)…”
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  11. 11
    Targeting Trypanosoma brucei FPPS by Fragment-based drug discovery

    Targeting Trypanosoma brucei FPPS by Fragment-based drug discovery Yazar: Münzker Lena

    Baskı/Yayın Bilgisi 2019
    Diğer Yazarlar: “…Klebe, Gerhard (Prof. Dr.)…”
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  12. 12
    The Power of Fragments: FBLD approach to investigate protein structures

    The Power of Fragments: FBLD approach to investigate protein structures Yazar: Magari, Francesca

    Baskı/Yayın Bilgisi 2020
    Diğer Yazarlar: “…Klebe, Gerhard (Prof. Dr.)…”
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  13. 13
    Identifizierung, Charakterisierung und Untersuchungen der Struktur-Wirkungs-Beziehung sowie des Mode of Action eines neuen antimikrobiellen Peptids aus Hirudo verbana

    Identifizierung, Charakterisierung und Untersuchungen der Struktur-Wirkungs-Beziehung sowie des Mode of Action eines neuen antimikrobiellen Peptids aus Hirudo verbana Yazar: Müller, Daniela

    Baskı/Yayın Bilgisi 2019
    Diğer Yazarlar: “…Klebe, Gerhard (Prof. Dr. rer. nat.)…”
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  14. 14
    Expanding the Toolbox for Computational Analysis in Rational Drug Discovery: Using Biomolecular Solvation to Predict Thermodynamic, Kinetic and Structural Properties of Protein-Ligand Complexes

    Expanding the Toolbox for Computational Analysis in Rational Drug Discovery: Using Biomolecular Solvation to Predict Thermodynamic, Kinetic and Structural Properties of Protein-Lig... Yazar: Hüfner, Tobias

    Baskı/Yayın Bilgisi 2019
    Diğer Yazarlar: “…Klebe, Gerhard (Prof. Dr.)…”
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  15. 15
    Inhibitor Synthesis and Biophysical Characterization of Protein–Ligand–Solvent Interactions An Analysis of the Thermodynamics and Kinetics of Ligand Binding to Thermolysin

    Inhibitor Synthesis and Biophysical Characterization of Protein–Ligand–Solvent Interactions An Analysis of the Thermodynamics and Kinetics of Ligand Binding to Thermolysin Yazar: Cramer, Jonathan

    Baskı/Yayın Bilgisi 2017
    Diğer Yazarlar: “…Klebe, Gerhard (Prof. Dr.)…”
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  16. 16
    Characterisation and differentiation of kinase binding pockets in PKA and PIM1 by small molecule fragments using protein crystallography

    Characterisation and differentiation of kinase binding pockets in PKA and PIM1 by small molecule fragments using protein crystallography Yazar: Siefker, Christof

    Baskı/Yayın Bilgisi 2018
    Diğer Yazarlar: “…Klebe, Gerhard (Prof. Dr.)…”
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  17. 17
    Structural Characterization of 17β-Hydroxysteroid Dehydrogenase Type 14 and Inhibitor Optimization Using Crystallography and Computational Techniques

    Structural Characterization of 17β-Hydroxysteroid Dehydrogenase Type 14 and Inhibitor Optimization Using Crystallography and Computational Techniques Yazar: Bertoletti, Nicole

    Baskı/Yayın Bilgisi 2017
    Diğer Yazarlar: “…Klebe, Gerhard (Prof. Dr.)…”
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  18. 18
    Proteindynamik - Flexibilität in Zielproteinen des strukturbasierten Wirkstoffdesigns

    Proteindynamik - Flexibilität in Zielproteinen des strukturbasierten Wirkstoffdesigns Yazar: Terwesten, Felix

    Baskı/Yayın Bilgisi 2017
    Diğer Yazarlar: “…Klebe, Gerhard (Prof. Dr.)…”
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  19. 19
    Erkennen von Proteinoberflächen durch ungewöhnliche Substrat-analoge Inhibitoren am Beispiel der cAMP-abhängigen Proteinkinase A

    Erkennen von Proteinoberflächen durch ungewöhnliche Substrat-analoge Inhibitoren am Beispiel der cAMP-abhängigen Proteinkinase A Yazar: Müller, Janis

    Baskı/Yayın Bilgisi 2017
    Diğer Yazarlar: “…Klebe, Gerhard (Prof. Dr.)…”
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  20. 20
    Systematic Correlation of Structural, Thermodynamic and Residual Solvation Properties of Hydrophobic Substituents in Hydrophobic Pockets Using Thermolysin as a Case Study

    Systematic Correlation of Structural, Thermodynamic and Residual Solvation Properties of Hydrophobic Substituents in Hydrophobic Pockets Using Thermolysin as a Case Study Yazar: Krimmer, Stefan Günter

    Baskı/Yayın Bilgisi 2017
    Diğer Yazarlar: “…Klebe, Gerhard (Prof. Dr.)…”
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