Ohcanbohtosat - Klebe, Gerhard (Prof. Dr.)

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  1. 1
    Leitstruktursuche mithilfe eines kristallographischen Fragment-Screenings zur Inhibierung des Klasse-II-Chaperons IpgC aus Shigella flexneri

    Leitstruktursuche mithilfe eines kristallographischen Fragment-Screenings zur Inhibierung des Klasse-II-Chaperons IpgC aus Shigella flexneri Dahkki Gárdonyi, Marina

    Almmustuhtton 2021
    Eará dahkkit: “… Klebe, Gerhard (Prof. Dr.) …”
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  2. 2
    Optimization of the Drug Design Process by Ligand Preorganization and Occupancy of Transient Binding Pockets Based on the Model Proteins Thrombin and Aldose Reductase

    Optimization of the Drug Design Process by Ligand Preorganization and Occupancy of Transient Binding Pockets Based on the Model Proteins Thrombin and Aldose Reductase Dahkki Sandner, Anna Sophie

    Almmustuhtton 2022
    Eará dahkkit: “… Klebe, Gerhard (Prof. Dr.) …”
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  3. 3
    Mutational Studies on 17β-HSD14, Serial Synchrotron X-ray Crystallography, Solubility Enhancement using Cyclodextrins and Fragment-Based Drug Discovery Multiple Blocks to Pave the Road of Drug Design

    Mutational Studies on 17β-HSD14, Serial Synchrotron X-ray Crystallography, Solubility Enhancement using Cyclodextrins and Fragment-Based Drug Discovery Multiple Blocks to Pave the... Dahkki Badran, Mohammed

    Almmustuhtton 2021
    Eará dahkkit: “… Klebe, Gerhard (Prof. Dr.) …”
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  4. 4
    Neue Ansätze zur Entwicklung von Modulatoren der homodimeren tRNA-Guanin-Transglycosylase

    Neue Ansätze zur Entwicklung von Modulatoren der homodimeren tRNA-Guanin-Transglycosylase Dahkki Nguyen, Andreas

    Almmustuhtton 2020
    Eará dahkkit: “… Klebe, Gerhard (Prof. Dr.) …”
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  5. 5
    Fragment-basierte Leitstruktursuche am Beispiel der Proteinkinase A

    Fragment-basierte Leitstruktursuche am Beispiel der Proteinkinase A Dahkki Oebbeke, Matthias

    Almmustuhtton 2021
    Eará dahkkit: “… Klebe, Gerhard (Prof. Dr.) …”
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  6. 6
    From Serendipity to the Rational Design of Protein–Protein Interface Modulators Targeting a tRNA-Modifying Enzyme

    From Serendipity to the Rational Design of Protein–Protein Interface Modulators Targeting a tRNA-Modifying Enzyme Dahkki Nguyen, Dzung

    Almmustuhtton 2020
    Eará dahkkit: “… Klebe, Gerhard (Prof. Dr.) …”
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  7. 7
    Thermodynamic, Kinetic and Crystallographic Investigations of Benzenesulfonamides as Ligands of Human Carbonic Anhydrase II

    Thermodynamic, Kinetic and Crystallographic Investigations of Benzenesulfonamides as Ligands of Human Carbonic Anhydrase II Dahkki Glöckner, Steffen

    Almmustuhtton 2020
    Eará dahkkit: “… Klebe, Gerhard Prof. Dr. …”
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  8. 8
    Do All Roads Really Lead to Rome? Learnings from Comparative Analysis using SPR, NMR, & X-Ray Crystallography to Optimize Fragment Screening in Drug Discovery.

    Do All Roads Really Lead to Rome? Learnings from Comparative Analysis using SPR, NMR, & X-Ray Crystallography to Optimize Fragment Screening in Drug Discovery. Dahkki Hassaan, Engi

    Almmustuhtton 2019
    Eará dahkkit: “… Klebe, Gerhard (Prof. Dr.) …”
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  9. 9
    Synthese von D-Phe/D-DiPhe-Pro-basierenden Liganden und deren biophysikalischen Charakterisierung zur Selektivitätsstudie von Thrombin und Trypsin sowie ein synthetischer Beitrag zur Darstellung von Inhibitoren der Aldose-Reduktase und Carboanhydrase II

    Synthese von D-Phe/D-DiPhe-Pro-basierenden Liganden und deren biophysikalischen Charakterisierung zur Selektivitätsstudie von Thrombin und Trypsin sowie ein synthetischer Beitrag z... Dahkki Ngo, Trong Khang

    Almmustuhtton 2020
    Eará dahkkit: “… Klebe, Gerhard (Prof. Dr.) …”
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  10. 10
    Targeting farnesyl pyrophosphate synthase of Trypanosoma cruzi by fragment-based lead discovery

    Targeting farnesyl pyrophosphate synthase of Trypanosoma cruzi by fragment-based lead discovery Dahkki Petrick, Joy Kristin

    Almmustuhtton 2019
    Eará dahkkit: “… Klebe, Gerhard (Prof. Dr.) …”
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  11. 11
    Targeting Trypanosoma brucei FPPS by Fragment-based drug discovery

    Targeting Trypanosoma brucei FPPS by Fragment-based drug discovery Dahkki Münzker Lena

    Almmustuhtton 2019
    Eará dahkkit: “… Klebe, Gerhard (Prof. Dr.) …”
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  12. 12
    The Power of Fragments: FBLD approach to investigate protein structures

    The Power of Fragments: FBLD approach to investigate protein structures Dahkki Magari, Francesca

    Almmustuhtton 2020
    Eará dahkkit: “… Klebe, Gerhard (Prof. Dr.) …”
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  13. 13
    Identifizierung, Charakterisierung und Untersuchungen der Struktur-Wirkungs-Beziehung sowie des Mode of Action eines neuen antimikrobiellen Peptids aus Hirudo verbana

    Identifizierung, Charakterisierung und Untersuchungen der Struktur-Wirkungs-Beziehung sowie des Mode of Action eines neuen antimikrobiellen Peptids aus Hirudo verbana Dahkki Müller, Daniela

    Almmustuhtton 2019
    Eará dahkkit: “… Klebe, Gerhard (Prof. Dr. rer. nat.) …”
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  14. 14
    Expanding the Toolbox for Computational Analysis in Rational Drug Discovery: Using Biomolecular Solvation to Predict Thermodynamic, Kinetic and Structural Properties of Protein-Ligand Complexes

    Expanding the Toolbox for Computational Analysis in Rational Drug Discovery: Using Biomolecular Solvation to Predict Thermodynamic, Kinetic and Structural Properties of Protein-Lig... Dahkki Hüfner, Tobias

    Almmustuhtton 2019
    Eará dahkkit: “… Klebe, Gerhard (Prof. Dr.) …”
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  15. 15
    Inhibitor Synthesis and Biophysical Characterization of Protein–Ligand–Solvent Interactions An Analysis of the Thermodynamics and Kinetics of Ligand Binding to Thermolysin

    Inhibitor Synthesis and Biophysical Characterization of Protein–Ligand–Solvent Interactions An Analysis of the Thermodynamics and Kinetics of Ligand Binding to Thermolysin Dahkki Cramer, Jonathan

    Almmustuhtton 2017
    Eará dahkkit: “… Klebe, Gerhard (Prof. Dr.) …”
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  16. 16
    Characterisation and differentiation of kinase binding pockets in PKA and PIM1 by small molecule fragments using protein crystallography

    Characterisation and differentiation of kinase binding pockets in PKA and PIM1 by small molecule fragments using protein crystallography Dahkki Siefker, Christof

    Almmustuhtton 2018
    Eará dahkkit: “… Klebe, Gerhard (Prof. Dr.) …”
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  17. 17
    Structural Characterization of 17β-Hydroxysteroid Dehydrogenase Type 14 and Inhibitor Optimization Using Crystallography and Computational Techniques

    Structural Characterization of 17β-Hydroxysteroid Dehydrogenase Type 14 and Inhibitor Optimization Using Crystallography and Computational Techniques Dahkki Bertoletti, Nicole

    Almmustuhtton 2017
    Eará dahkkit: “… Klebe, Gerhard (Prof. Dr.) …”
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  18. 18
    Proteindynamik - Flexibilität in Zielproteinen des strukturbasierten Wirkstoffdesigns

    Proteindynamik - Flexibilität in Zielproteinen des strukturbasierten Wirkstoffdesigns Dahkki Terwesten, Felix

    Almmustuhtton 2017
    Eará dahkkit: “… Klebe, Gerhard (Prof. Dr.) …”
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  19. 19
    Erkennen von Proteinoberflächen durch ungewöhnliche Substrat-analoge Inhibitoren am Beispiel der cAMP-abhängigen Proteinkinase A

    Erkennen von Proteinoberflächen durch ungewöhnliche Substrat-analoge Inhibitoren am Beispiel der cAMP-abhängigen Proteinkinase A Dahkki Müller, Janis

    Almmustuhtton 2017
    Eará dahkkit: “… Klebe, Gerhard (Prof. Dr.) …”
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  20. 20
    Systematic Correlation of Structural, Thermodynamic and Residual Solvation Properties of Hydrophobic Substituents in Hydrophobic Pockets Using Thermolysin as a Case Study

    Systematic Correlation of Structural, Thermodynamic and Residual Solvation Properties of Hydrophobic Substituents in Hydrophobic Pockets Using Thermolysin as a Case Study Dahkki Krimmer, Stefan Günter

    Almmustuhtton 2017
    Eará dahkkit: “… Klebe, Gerhard (Prof. Dr.) …”
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