Ngā hua rapu - Klebe, Gerhard (Prof. Dr.)

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  1. 1
    Leitstruktursuche mithilfe eines kristallographischen Fragment-Screenings zur Inhibierung des Klasse-II-Chaperons IpgC aus Shigella flexneri

    Leitstruktursuche mithilfe eines kristallographischen Fragment-Screenings zur Inhibierung des Klasse-II-Chaperons IpgC aus Shigella flexneri mā Gárdonyi, Marina

    I whakaputaina 2021
    Ētahi atu kaituhi: “… Klebe, Gerhard (Prof. Dr.) …”
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  2. 2
    Optimization of the Drug Design Process by Ligand Preorganization and Occupancy of Transient Binding Pockets Based on the Model Proteins Thrombin and Aldose Reductase

    Optimization of the Drug Design Process by Ligand Preorganization and Occupancy of Transient Binding Pockets Based on the Model Proteins Thrombin and Aldose Reductase mā Sandner, Anna Sophie

    I whakaputaina 2022
    Ētahi atu kaituhi: “… Klebe, Gerhard (Prof. Dr.) …”
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  3. 3
    Mutational Studies on 17β-HSD14, Serial Synchrotron X-ray Crystallography, Solubility Enhancement using Cyclodextrins and Fragment-Based Drug Discovery Multiple Blocks to Pave the Road of Drug Design

    Mutational Studies on 17β-HSD14, Serial Synchrotron X-ray Crystallography, Solubility Enhancement using Cyclodextrins and Fragment-Based Drug Discovery Multiple Blocks to Pave the... mā Badran, Mohammed

    I whakaputaina 2021
    Ētahi atu kaituhi: “… Klebe, Gerhard (Prof. Dr.) …”
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  4. 4
    Neue Ansätze zur Entwicklung von Modulatoren der homodimeren tRNA-Guanin-Transglycosylase

    Neue Ansätze zur Entwicklung von Modulatoren der homodimeren tRNA-Guanin-Transglycosylase mā Nguyen, Andreas

    I whakaputaina 2020
    Ētahi atu kaituhi: “… Klebe, Gerhard (Prof. Dr.) …”
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  5. 5
    Fragment-basierte Leitstruktursuche am Beispiel der Proteinkinase A

    Fragment-basierte Leitstruktursuche am Beispiel der Proteinkinase A mā Oebbeke, Matthias

    I whakaputaina 2021
    Ētahi atu kaituhi: “… Klebe, Gerhard (Prof. Dr.) …”
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  6. 6
    From Serendipity to the Rational Design of Protein–Protein Interface Modulators Targeting a tRNA-Modifying Enzyme

    From Serendipity to the Rational Design of Protein–Protein Interface Modulators Targeting a tRNA-Modifying Enzyme mā Nguyen, Dzung

    I whakaputaina 2020
    Ētahi atu kaituhi: “… Klebe, Gerhard (Prof. Dr.) …”
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  7. 7
    Thermodynamic, Kinetic and Crystallographic Investigations of Benzenesulfonamides as Ligands of Human Carbonic Anhydrase II

    Thermodynamic, Kinetic and Crystallographic Investigations of Benzenesulfonamides as Ligands of Human Carbonic Anhydrase II mā Glöckner, Steffen

    I whakaputaina 2020
    Ētahi atu kaituhi: “… Klebe, Gerhard Prof. Dr. …”
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  8. 8
    Do All Roads Really Lead to Rome? Learnings from Comparative Analysis using SPR, NMR, & X-Ray Crystallography to Optimize Fragment Screening in Drug Discovery.

    Do All Roads Really Lead to Rome? Learnings from Comparative Analysis using SPR, NMR, & X-Ray Crystallography to Optimize Fragment Screening in Drug Discovery. mā Hassaan, Engi

    I whakaputaina 2019
    Ētahi atu kaituhi: “… Klebe, Gerhard (Prof. Dr.) …”
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  9. 9
    Synthese von D-Phe/D-DiPhe-Pro-basierenden Liganden und deren biophysikalischen Charakterisierung zur Selektivitätsstudie von Thrombin und Trypsin sowie ein synthetischer Beitrag zur Darstellung von Inhibitoren der Aldose-Reduktase und Carboanhydrase II

    Synthese von D-Phe/D-DiPhe-Pro-basierenden Liganden und deren biophysikalischen Charakterisierung zur Selektivitätsstudie von Thrombin und Trypsin sowie ein synthetischer Beitrag z... mā Ngo, Trong Khang

    I whakaputaina 2020
    Ētahi atu kaituhi: “… Klebe, Gerhard (Prof. Dr.) …”
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  10. 10
    Targeting farnesyl pyrophosphate synthase of Trypanosoma cruzi by fragment-based lead discovery

    Targeting farnesyl pyrophosphate synthase of Trypanosoma cruzi by fragment-based lead discovery mā Petrick, Joy Kristin

    I whakaputaina 2019
    Ētahi atu kaituhi: “… Klebe, Gerhard (Prof. Dr.) …”
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  11. 11
    Targeting Trypanosoma brucei FPPS by Fragment-based drug discovery

    Targeting Trypanosoma brucei FPPS by Fragment-based drug discovery mā Münzker Lena

    I whakaputaina 2019
    Ētahi atu kaituhi: “… Klebe, Gerhard (Prof. Dr.) …”
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  12. 12
    The Power of Fragments: FBLD approach to investigate protein structures

    The Power of Fragments: FBLD approach to investigate protein structures mā Magari, Francesca

    I whakaputaina 2020
    Ētahi atu kaituhi: “… Klebe, Gerhard (Prof. Dr.) …”
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  13. 13
    Identifizierung, Charakterisierung und Untersuchungen der Struktur-Wirkungs-Beziehung sowie des Mode of Action eines neuen antimikrobiellen Peptids aus Hirudo verbana

    Identifizierung, Charakterisierung und Untersuchungen der Struktur-Wirkungs-Beziehung sowie des Mode of Action eines neuen antimikrobiellen Peptids aus Hirudo verbana mā Müller, Daniela

    I whakaputaina 2019
    Ētahi atu kaituhi: “… Klebe, Gerhard (Prof. Dr. rer. nat.) …”
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  14. 14
    Expanding the Toolbox for Computational Analysis in Rational Drug Discovery: Using Biomolecular Solvation to Predict Thermodynamic, Kinetic and Structural Properties of Protein-Ligand Complexes

    Expanding the Toolbox for Computational Analysis in Rational Drug Discovery: Using Biomolecular Solvation to Predict Thermodynamic, Kinetic and Structural Properties of Protein-Lig... mā Hüfner, Tobias

    I whakaputaina 2019
    Ētahi atu kaituhi: “… Klebe, Gerhard (Prof. Dr.) …”
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  15. 15
    Inhibitor Synthesis and Biophysical Characterization of Protein–Ligand–Solvent Interactions An Analysis of the Thermodynamics and Kinetics of Ligand Binding to Thermolysin

    Inhibitor Synthesis and Biophysical Characterization of Protein–Ligand–Solvent Interactions An Analysis of the Thermodynamics and Kinetics of Ligand Binding to Thermolysin mā Cramer, Jonathan

    I whakaputaina 2017
    Ētahi atu kaituhi: “… Klebe, Gerhard (Prof. Dr.) …”
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  16. 16
    Characterisation and differentiation of kinase binding pockets in PKA and PIM1 by small molecule fragments using protein crystallography

    Characterisation and differentiation of kinase binding pockets in PKA and PIM1 by small molecule fragments using protein crystallography mā Siefker, Christof

    I whakaputaina 2018
    Ētahi atu kaituhi: “… Klebe, Gerhard (Prof. Dr.) …”
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  17. 17
    Structural Characterization of 17β-Hydroxysteroid Dehydrogenase Type 14 and Inhibitor Optimization Using Crystallography and Computational Techniques

    Structural Characterization of 17β-Hydroxysteroid Dehydrogenase Type 14 and Inhibitor Optimization Using Crystallography and Computational Techniques mā Bertoletti, Nicole

    I whakaputaina 2017
    Ētahi atu kaituhi: “… Klebe, Gerhard (Prof. Dr.) …”
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  18. 18
    Proteindynamik - Flexibilität in Zielproteinen des strukturbasierten Wirkstoffdesigns

    Proteindynamik - Flexibilität in Zielproteinen des strukturbasierten Wirkstoffdesigns mā Terwesten, Felix

    I whakaputaina 2017
    Ētahi atu kaituhi: “… Klebe, Gerhard (Prof. Dr.) …”
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  19. 19
    Erkennen von Proteinoberflächen durch ungewöhnliche Substrat-analoge Inhibitoren am Beispiel der cAMP-abhängigen Proteinkinase A

    Erkennen von Proteinoberflächen durch ungewöhnliche Substrat-analoge Inhibitoren am Beispiel der cAMP-abhängigen Proteinkinase A mā Müller, Janis

    I whakaputaina 2017
    Ētahi atu kaituhi: “… Klebe, Gerhard (Prof. Dr.) …”
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  20. 20
    Systematic Correlation of Structural, Thermodynamic and Residual Solvation Properties of Hydrophobic Substituents in Hydrophobic Pockets Using Thermolysin as a Case Study

    Systematic Correlation of Structural, Thermodynamic and Residual Solvation Properties of Hydrophobic Substituents in Hydrophobic Pockets Using Thermolysin as a Case Study mā Krimmer, Stefan Günter

    I whakaputaina 2017
    Ētahi atu kaituhi: “… Klebe, Gerhard (Prof. Dr.) …”
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