検索結果 - Klebe, Gerhard (Prof. Dr.)

Leitstruktursuche mithilfe eines kristallographischen Fragment-Screenings zur Inhibierung des Klasse-II-Chaperons IpgC aus Shigella flexneri 著者: Gárdonyi, Marina

その他の著者: “…Klebe, Gerhard (Prof. Dr.)…”
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Optimization of the Drug Design Process by Ligand Preorganization and Occupancy of Transient Binding Pockets Based on the Model Proteins Thrombin and Aldose Reductase 著者: Sandner, Anna Sophie

その他の著者: “…Klebe, Gerhard (Prof. Dr.)…”
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Mutational Studies on 17β-HSD14, Serial Synchrotron X-ray Crystallography, Solubility Enhancement using Cyclodextrins and Fragment-Based Drug Discovery Multiple Blocks to Pave the... 著者: Badran, Mohammed

その他の著者: “…Klebe, Gerhard (Prof. Dr.)…”
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Neue Ansätze zur Entwicklung von Modulatoren der homodimeren tRNA-Guanin-Transglycosylase 著者: Nguyen, Andreas

その他の著者: “…Klebe, Gerhard (Prof. Dr.)…”
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Fragment-basierte Leitstruktursuche am Beispiel der Proteinkinase A 著者: Oebbeke, Matthias

その他の著者: “…Klebe, Gerhard (Prof. Dr.)…”
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From Serendipity to the Rational Design of Protein–Protein Interface Modulators Targeting a tRNA-Modifying Enzyme 著者: Nguyen, Dzung

その他の著者: “…Klebe, Gerhard (Prof. Dr.)…”
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Thermodynamic, Kinetic and Crystallographic Investigations of Benzenesulfonamides as Ligands of Human Carbonic Anhydrase II 著者: Glöckner, Steffen

その他の著者: “…Klebe, Gerhard Prof. Dr.…”
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Do All Roads Really Lead to Rome? Learnings from Comparative Analysis using SPR, NMR, & X-Ray Crystallography to Optimize Fragment Screening in Drug Discovery. 著者: Hassaan, Engi

その他の著者: “…Klebe, Gerhard (Prof. Dr.)…”
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Synthese von D-Phe/D-DiPhe-Pro-basierenden Liganden und deren biophysikalischen Charakterisierung zur Selektivitätsstudie von Thrombin und Trypsin sowie ein synthetischer Beitrag z... 著者: Ngo, Trong Khang

その他の著者: “…Klebe, Gerhard (Prof. Dr.)…”
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Targeting farnesyl pyrophosphate synthase of Trypanosoma cruzi by fragment-based lead discovery 著者: Petrick, Joy Kristin

その他の著者: “…Klebe, Gerhard (Prof. Dr.)…”
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Targeting Trypanosoma brucei FPPS by Fragment-based drug discovery 著者: Münzker Lena

その他の著者: “…Klebe, Gerhard (Prof. Dr.)…”
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The Power of Fragments: FBLD approach to investigate protein structures 著者: Magari, Francesca

その他の著者: “…Klebe, Gerhard (Prof. Dr.)…”
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Identifizierung, Charakterisierung und Untersuchungen der Struktur-Wirkungs-Beziehung sowie des Mode of Action eines neuen antimikrobiellen Peptids aus Hirudo verbana 著者: Müller, Daniela

その他の著者: “…Klebe, Gerhard (Prof. Dr. rer. nat.)…”
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Expanding the Toolbox for Computational Analysis in Rational Drug Discovery: Using Biomolecular Solvation to Predict Thermodynamic, Kinetic and Structural Properties of Protein-Lig... 著者: Hüfner, Tobias

その他の著者: “…Klebe, Gerhard (Prof. Dr.)…”
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Inhibitor Synthesis and Biophysical Characterization of Protein–Ligand–Solvent Interactions An Analysis of the Thermodynamics and Kinetics of Ligand Binding to Thermolysin 著者: Cramer, Jonathan

その他の著者: “…Klebe, Gerhard (Prof. Dr.)…”
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Characterisation and differentiation of kinase binding pockets in PKA and PIM1 by small molecule fragments using protein crystallography 著者: Siefker, Christof

その他の著者: “…Klebe, Gerhard (Prof. Dr.)…”
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Structural Characterization of 17β-Hydroxysteroid Dehydrogenase Type 14 and Inhibitor Optimization Using Crystallography and Computational Techniques 著者: Bertoletti, Nicole

その他の著者: “…Klebe, Gerhard (Prof. Dr.)…”
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Proteindynamik - Flexibilität in Zielproteinen des strukturbasierten Wirkstoffdesigns 著者: Terwesten, Felix

その他の著者: “…Klebe, Gerhard (Prof. Dr.)…”
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Erkennen von Proteinoberflächen durch ungewöhnliche Substrat-analoge Inhibitoren am Beispiel der cAMP-abhängigen Proteinkinase A 著者: Müller, Janis

その他の著者: “…Klebe, Gerhard (Prof. Dr.)…”
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Systematic Correlation of Structural, Thermodynamic and Residual Solvation Properties of Hydrophobic Substituents in Hydrophobic Pockets Using Thermolysin as a Case Study 著者: Krimmer, Stefan Günter

その他の著者: “…Klebe, Gerhard (Prof. Dr.)…”
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