Torthaí cuardaigh - Klebe, Gerhard (Prof. Dr.)

Beachtaigh na torthaí
  1. 1
    Leitstruktursuche mithilfe eines kristallographischen Fragment-Screenings zur Inhibierung des Klasse-II-Chaperons IpgC aus Shigella flexneri

    Leitstruktursuche mithilfe eines kristallographischen Fragment-Screenings zur Inhibierung des Klasse-II-Chaperons IpgC aus Shigella flexneri de réir Gárdonyi, Marina

    Foilsithe / Cruthaithe 2021
    Rannpháirtithe: “…Klebe, Gerhard (Prof. Dr.)…”
    An téacs iomlán mar PDF
    Dissertation
    Cuir le mo chuid Ceanán
    Sábháilte in:
  2. 2
    Optimization of the Drug Design Process by Ligand Preorganization and Occupancy of Transient Binding Pockets Based on the Model Proteins Thrombin and Aldose Reductase

    Optimization of the Drug Design Process by Ligand Preorganization and Occupancy of Transient Binding Pockets Based on the Model Proteins Thrombin and Aldose Reductase de réir Sandner, Anna Sophie

    Foilsithe / Cruthaithe 2022
    Rannpháirtithe: “…Klebe, Gerhard (Prof. Dr.)…”
    An téacs iomlán mar PDF
    Dissertation
    Cuir le mo chuid Ceanán
    Sábháilte in:
  3. 3
    Mutational Studies on 17β-HSD14, Serial Synchrotron X-ray Crystallography, Solubility Enhancement using Cyclodextrins and Fragment-Based Drug Discovery Multiple Blocks to Pave the Road of Drug Design

    Mutational Studies on 17β-HSD14, Serial Synchrotron X-ray Crystallography, Solubility Enhancement using Cyclodextrins and Fragment-Based Drug Discovery Multiple Blocks to Pave the... de réir Badran, Mohammed

    Foilsithe / Cruthaithe 2021
    Rannpháirtithe: “…Klebe, Gerhard (Prof. Dr.)…”
    An téacs iomlán mar PDF
    Dissertation
    Cuir le mo chuid Ceanán
    Sábháilte in:
  4. 4
    Neue Ansätze zur Entwicklung von Modulatoren der homodimeren tRNA-Guanin-Transglycosylase

    Neue Ansätze zur Entwicklung von Modulatoren der homodimeren tRNA-Guanin-Transglycosylase de réir Nguyen, Andreas

    Foilsithe / Cruthaithe 2020
    Rannpháirtithe: “…Klebe, Gerhard (Prof. Dr.)…”
    An téacs iomlán mar PDF
    Dissertation
    Cuir le mo chuid Ceanán
    Sábháilte in:
  5. 5
    Fragment-basierte Leitstruktursuche am Beispiel der Proteinkinase A

    Fragment-basierte Leitstruktursuche am Beispiel der Proteinkinase A de réir Oebbeke, Matthias

    Foilsithe / Cruthaithe 2021
    Rannpháirtithe: “…Klebe, Gerhard (Prof. Dr.)…”
    An téacs iomlán mar PDF
    Dissertation
    Cuir le mo chuid Ceanán
    Sábháilte in:
  6. 6
    From Serendipity to the Rational Design of Protein–Protein Interface Modulators Targeting a tRNA-Modifying Enzyme

    From Serendipity to the Rational Design of Protein–Protein Interface Modulators Targeting a tRNA-Modifying Enzyme de réir Nguyen, Dzung

    Foilsithe / Cruthaithe 2020
    Rannpháirtithe: “…Klebe, Gerhard (Prof. Dr.)…”
    An téacs iomlán mar PDF
    Dissertation
    Cuir le mo chuid Ceanán
    Sábháilte in:
  7. 7
    Thermodynamic, Kinetic and Crystallographic Investigations of Benzenesulfonamides as Ligands of Human Carbonic Anhydrase II

    Thermodynamic, Kinetic and Crystallographic Investigations of Benzenesulfonamides as Ligands of Human Carbonic Anhydrase II de réir Glöckner, Steffen

    Foilsithe / Cruthaithe 2020
    Rannpháirtithe: “…Klebe, Gerhard Prof. Dr.…”
    An téacs iomlán mar PDF
    Dissertation
    Cuir le mo chuid Ceanán
    Sábháilte in:
  8. 8
    Do All Roads Really Lead to Rome? Learnings from Comparative Analysis using SPR, NMR, & X-Ray Crystallography to Optimize Fragment Screening in Drug Discovery.

    Do All Roads Really Lead to Rome? Learnings from Comparative Analysis using SPR, NMR, & X-Ray Crystallography to Optimize Fragment Screening in Drug Discovery. de réir Hassaan, Engi

    Foilsithe / Cruthaithe 2019
    Rannpháirtithe: “…Klebe, Gerhard (Prof. Dr.)…”
    An téacs iomlán mar PDF
    Dissertation
    Cuir le mo chuid Ceanán
    Sábháilte in:
  9. 9
    Synthese von D-Phe/D-DiPhe-Pro-basierenden Liganden und deren biophysikalischen Charakterisierung zur Selektivitätsstudie von Thrombin und Trypsin sowie ein synthetischer Beitrag zur Darstellung von Inhibitoren der Aldose-Reduktase und Carboanhydrase II

    Synthese von D-Phe/D-DiPhe-Pro-basierenden Liganden und deren biophysikalischen Charakterisierung zur Selektivitätsstudie von Thrombin und Trypsin sowie ein synthetischer Beitrag z... de réir Ngo, Trong Khang

    Foilsithe / Cruthaithe 2020
    Rannpháirtithe: “…Klebe, Gerhard (Prof. Dr.)…”
    An téacs iomlán mar PDF
    Dissertation
    Cuir le mo chuid Ceanán
    Sábháilte in:
  10. 10
    Targeting farnesyl pyrophosphate synthase of Trypanosoma cruzi by fragment-based lead discovery

    Targeting farnesyl pyrophosphate synthase of Trypanosoma cruzi by fragment-based lead discovery de réir Petrick, Joy Kristin

    Foilsithe / Cruthaithe 2019
    Rannpháirtithe: “…Klebe, Gerhard (Prof. Dr.)…”
    An téacs iomlán mar PDF
    Dissertation
    Cuir le mo chuid Ceanán
    Sábháilte in:
  11. 11
    Targeting Trypanosoma brucei FPPS by Fragment-based drug discovery

    Targeting Trypanosoma brucei FPPS by Fragment-based drug discovery de réir Münzker Lena

    Foilsithe / Cruthaithe 2019
    Rannpháirtithe: “…Klebe, Gerhard (Prof. Dr.)…”
    An téacs iomlán mar PDF
    Dissertation
    Cuir le mo chuid Ceanán
    Sábháilte in:
  12. 12
    The Power of Fragments: FBLD approach to investigate protein structures

    The Power of Fragments: FBLD approach to investigate protein structures de réir Magari, Francesca

    Foilsithe / Cruthaithe 2020
    Rannpháirtithe: “…Klebe, Gerhard (Prof. Dr.)…”
    An téacs iomlán mar PDF
    Dissertation
    Cuir le mo chuid Ceanán
    Sábháilte in:
  13. 13
    Identifizierung, Charakterisierung und Untersuchungen der Struktur-Wirkungs-Beziehung sowie des Mode of Action eines neuen antimikrobiellen Peptids aus Hirudo verbana

    Identifizierung, Charakterisierung und Untersuchungen der Struktur-Wirkungs-Beziehung sowie des Mode of Action eines neuen antimikrobiellen Peptids aus Hirudo verbana de réir Müller, Daniela

    Foilsithe / Cruthaithe 2019
    Rannpháirtithe: “…Klebe, Gerhard (Prof. Dr. rer. nat.)…”
    An téacs iomlán mar PDF
    Dissertation
    Cuir le mo chuid Ceanán
    Sábháilte in:
  14. 14
    Expanding the Toolbox for Computational Analysis in Rational Drug Discovery: Using Biomolecular Solvation to Predict Thermodynamic, Kinetic and Structural Properties of Protein-Ligand Complexes

    Expanding the Toolbox for Computational Analysis in Rational Drug Discovery: Using Biomolecular Solvation to Predict Thermodynamic, Kinetic and Structural Properties of Protein-Lig... de réir Hüfner, Tobias

    Foilsithe / Cruthaithe 2019
    Rannpháirtithe: “…Klebe, Gerhard (Prof. Dr.)…”
    An téacs iomlán mar PDF
    Dissertation
    Cuir le mo chuid Ceanán
    Sábháilte in:
  15. 15
    Inhibitor Synthesis and Biophysical Characterization of Protein–Ligand–Solvent Interactions An Analysis of the Thermodynamics and Kinetics of Ligand Binding to Thermolysin

    Inhibitor Synthesis and Biophysical Characterization of Protein–Ligand–Solvent Interactions An Analysis of the Thermodynamics and Kinetics of Ligand Binding to Thermolysin de réir Cramer, Jonathan

    Foilsithe / Cruthaithe 2017
    Rannpháirtithe: “…Klebe, Gerhard (Prof. Dr.)…”
    An téacs iomlán mar PDF
    Dissertation
    Cuir le mo chuid Ceanán
    Sábháilte in:
  16. 16
    Characterisation and differentiation of kinase binding pockets in PKA and PIM1 by small molecule fragments using protein crystallography

    Characterisation and differentiation of kinase binding pockets in PKA and PIM1 by small molecule fragments using protein crystallography de réir Siefker, Christof

    Foilsithe / Cruthaithe 2018
    Rannpháirtithe: “…Klebe, Gerhard (Prof. Dr.)…”
    An téacs iomlán mar PDF
    Dissertation
    Cuir le mo chuid Ceanán
    Sábháilte in:
  17. 17
    Structural Characterization of 17β-Hydroxysteroid Dehydrogenase Type 14 and Inhibitor Optimization Using Crystallography and Computational Techniques

    Structural Characterization of 17β-Hydroxysteroid Dehydrogenase Type 14 and Inhibitor Optimization Using Crystallography and Computational Techniques de réir Bertoletti, Nicole

    Foilsithe / Cruthaithe 2017
    Rannpháirtithe: “…Klebe, Gerhard (Prof. Dr.)…”
    An téacs iomlán mar PDF
    Dissertation
    Cuir le mo chuid Ceanán
    Sábháilte in:
  18. 18
    Proteindynamik - Flexibilität in Zielproteinen des strukturbasierten Wirkstoffdesigns

    Proteindynamik - Flexibilität in Zielproteinen des strukturbasierten Wirkstoffdesigns de réir Terwesten, Felix

    Foilsithe / Cruthaithe 2017
    Rannpháirtithe: “…Klebe, Gerhard (Prof. Dr.)…”
    An téacs iomlán mar PDF
    Dissertation
    Cuir le mo chuid Ceanán
    Sábháilte in:
  19. 19
    Erkennen von Proteinoberflächen durch ungewöhnliche Substrat-analoge Inhibitoren am Beispiel der cAMP-abhängigen Proteinkinase A

    Erkennen von Proteinoberflächen durch ungewöhnliche Substrat-analoge Inhibitoren am Beispiel der cAMP-abhängigen Proteinkinase A de réir Müller, Janis

    Foilsithe / Cruthaithe 2017
    Rannpháirtithe: “…Klebe, Gerhard (Prof. Dr.)…”
    An téacs iomlán mar PDF
    Dissertation
    Cuir le mo chuid Ceanán
    Sábháilte in:
  20. 20
    Systematic Correlation of Structural, Thermodynamic and Residual Solvation Properties of Hydrophobic Substituents in Hydrophobic Pockets Using Thermolysin as a Case Study

    Systematic Correlation of Structural, Thermodynamic and Residual Solvation Properties of Hydrophobic Substituents in Hydrophobic Pockets Using Thermolysin as a Case Study de réir Krimmer, Stefan Günter

    Foilsithe / Cruthaithe 2017
    Rannpháirtithe: “…Klebe, Gerhard (Prof. Dr.)…”
    An téacs iomlán mar PDF
    Dissertation
    Cuir le mo chuid Ceanán
    Sábháilte in:

Uirlisí cuardaigh: