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Titel:The rationale for the treatment of long-Covid symptoms – A cardiologist's view
Autor:Schieffer, Elisabeth
Weitere Verfasser:Schieffer, Bernhard
Veröffentlicht:2022
URI:https://archiv.ub.uni-marburg.de/es/2023/0057
DOI: https://doi.org/10.3389/fcvm.2022.992686
URN: urn:nbn:de:hebis:04-es2023-00570
DDC:610 Medizin
Publikationsdatum:2023-05-16
Lizenz:https://creativecommons.org/licenses/by/4.0

Dokument

Schlagwörter:
lipid – hybrid nanoparticles, renin-angiotensin system, kalkrein-kinin system, histamin challenge, HDL - cholesterol, long-Covid syndrome, cholesterol

Summary:
The ongoing coronavirus disease 2019 pandemic left us with thousands of patients suffering from neurological, cardiovascular, and psychiatric disorders named post-acute sequelae of COVID-19 or just long-Covid. In parallel, the vaccination campaigns against SARS-CoV-2 spike protein saved millions of lives worldwide but long-Covid symptoms also appeared rarely following vaccination with a strong overlap to the “canonical” long-Covid symptoms. A therapeutic strategy targeting both, post-VAC and post-SARS-CoV-2 long-Covid symptoms is warranted since exposure to the S-protein either by vaccination or SARS-CoV-2 infection may trigger identical immuno-inflammatory cascades resulting in long-Covid symptoms.


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