Loss of the miR379-410 cluster in mice leads to alterations in social and anxiety-related behaviours

Loss of the miR379-410 cluster in mice leads to alterations in social and anxiety-related behaviours

microRNAs (miRNAs) belong to a group of small non-coding RNAs that down regulates gene expression at the post-transcriptional level. The paternally imprinted placental mammal-specific miR379-410 cluster hosts 38 miRNAs. In the last decade, several members of the cluster have been shown to regulate s...

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Detalles Bibliográficos
Autor Principal: Lackinger, Martin
Outros autores: Schratt, Gerhard (Prof. Dr.) (BetreuerIn (Doktorarbeit))
Formato: Dissertation
Idioma:inglés
Publicado: Philipps-Universität Marburg 2018
Schlagworte:
hippocampus
miR
Angstverhalten
Medizin
neurodevelopme
Sozialverhalten
mikroRNA
Verhalten
microRNA
knockout mouse
neur
Hippocampus
miRNA
Knockout-Maus
behaviour
Glutamatrezeptor
glutamate receptor
Synapse,synaptische Transmission
sociability
synaptic transmission
anxiety
synapse
Medical sciences Medicine
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