Elucidating the functional role of Dual-specificity Tyrosine Regulated Kinase 1B (DYRK1B) in the Hedgehog (Hh) Signaling Pathway.

Elucidating the functional role of Dual-specificity Tyrosine Regulated Kinase 1B (DYRK1B) in the Hedgehog (Hh) Signaling Pathway.

Hedgehog signaling (Hh) plays a crucial role in vital processes such as embryonic development or cell homeostasis. Aberrant Hh signaling is linked to formation, progression, and growth of tumors. The canonical Hh signaling cascade is initiated by binding of the Hh ligand to its receptor Patched1...

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Bibliografiske detaljer
Hovedforfatter: Singh, Rajeev
Andre forfattere: Lauth, Matthias (PD Dr.) (BetreuerIn (Doktorarbeit))
Format: Dissertation
Sprog:engelsk
Udgivet: Philipps-Universität Marburg 2018
Fag:
Oncology
DYRK Kinase
Tumor Signalwege
Molecular biology
Hedgehog Pathway
Molekularbiologie
Medizin
Tumor Signaling Pathways
Medical sciences Medicine
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