Structural Characterization of 17β-Hydroxysteroid Dehydrogenase Type 14 and Inhibitor Optimization Using Crystallography and Computational Techniques
17β-Hydroxysteroid dehydrogenase type 14 (17β-HSD14) is the latest identified subtype of 17β HSDs. In vivo this enzyme oxidizes the hydroxyl group at position 17 of estradiol (E2) and 5 androstenediol (5-diol) in the presence of NAD+ as cofactor. Two isoforms of this cytosolic protein exist that dif...
Spremljeno u:
Glavni autor: | |
---|---|
Daljnji autori: | |
Format: | Dissertation |
Jezik: | engleski |
Izdano: |
Philipps-Universität Marburg
2017
|
Teme: | |
Online pristup: | PDF cijeli tekst |
Oznake: |
Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!
|
No references were found for this record.