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The species-specific effects of guinea pig adaptive mutations in Marburg virus VP40 and L on the protein’s functions and viral fitness
Marburg virus (MARV) is a highly pathogenic virus that causes severe, often lethal diseases specifically in humans and non-human primates. In rodents MARV is non-pathogenic. However, sequential passaging of MARV in rodents results in selection of a rodent-lethal virus. Lofts et al. established a gui...
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| 格式: | Dissertation |
| 语言: | 英语 |
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Philipps-Universität Marburg
2017
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| 在线阅读: | PDF-Volltext |
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