The species-specific effects of guinea pig adaptive mutations in Marburg virus VP40 and L on the protein’s functions and viral fitness

Marburg virus (MARV) is a highly pathogenic virus that causes severe, often lethal diseases specifically in humans and non-human primates. In rodents MARV is non-pathogenic. However, sequential passaging of MARV in rodents results in selection of a rodent-lethal virus. Lofts et al. established a gui...

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Hovedforfatter: Köhler, Alexander
Andre forfattere: Becker, Stephan (Prof. Dr.) (BetreuerIn (Doktorarbeit))
Format: Dissertation
Sprog:engelsk
Udgivet: Philipps-Universität Marburg 2017
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