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The species-specific effects of guinea pig adaptive mutations in Marburg virus VP40 and L on the protein’s functions and viral fitness
Marburg virus (MARV) is a highly pathogenic virus that causes severe, often lethal diseases specifically in humans and non-human primates. In rodents MARV is non-pathogenic. However, sequential passaging of MARV in rodents results in selection of a rodent-lethal virus. Lofts et al. established a gui...
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| 主要作者: | |
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| 其他作者: | |
| 格式: | Dissertation |
| 語言: | 英语 |
| 出版: |
Philipps-Universität Marburg
2017
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| 主題: | |
| 在線閱讀: | PDF-Volltext |
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PDF-Volltext| 索引號: |
urn:nbn:de:hebis:04-z2017-03377 |
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| Publikationsdatum: |
2017-06-12 |
| Datum der Annahme: |
2017-05-10 |
| Downloads: |
49 (2024), 106 (2023), 97 (2022), 109 (2021), 122 (2020), 112 (2019), 40 (2018) |
| Lizenz: |
https://creativecommons.org/licenses/by-nc-sa/4.0 |
| Zugangs-URL: |
https://archiv.ub.uni-marburg.de/diss/z2017/0337 https://doi.org/10.17192/z2017.0337 |