Publikationsserver
Development of new immunoassay platforms for rapid serological diagnosis of Lyme borreliosis
The presented work describes the development of new ligand-binding assay platforms for rapid serological diagnosis. 3-D polyethylene sinter bodies and monodisperse gold nanoparticles have been successfully employed as protein carriers, providing sensitive, selective and rapid serological diagnosis....
Gorde:
| Egile nagusia: | |
|---|---|
| Beste egile batzuk: | |
| Formatua: | Dissertation |
| Hizkuntza: | ingelesa |
| Argitaratua: |
Philipps-Universität Marburg
2016
|
| Gaiak: | |
| Sarrera elektronikoa: | PDF testu osoa |
| Etiketak: |
Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!
|
| Gaia: | The presented work describes the development of new ligand-binding assay platforms for rapid serological diagnosis. 3-D polyethylene sinter bodies and monodisperse gold nanoparticles have been successfully employed as protein carriers, providing sensitive, selective and rapid serological diagnosis. Detection of anti-Borrelia antibodies in human sera samples was taken as a model in our work. Antibodies recognition either by visible observation or by spectroscopic measurements was easily practicable. All developed assays could be performed in a short time, 5-30 min, providing a suitable colorimetric point of care test. The established assays offer simple, rapid and reliable tools of analysis with minimal cost, which can be easily transferred to other infectious diseases. |
|---|---|
| DOI: | 10.17192/z2016.0497 |