Polymerase mutations promoting adaptation of avian influenza virus of subtype H9N2 to mammals

Polymerase mutations promoting adaptation of avian influenza virus of subtype H9N2 to mammals

Transmission of influenza viruses from aquatic birds to mammals is promoted by the adaptation of the viral proteins to the new host. This includes the PB2 subunit of the viral polymerase complex. This protein has been described as an important host range factor, able to modulate the virulence of inf...

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Bibliografiske detaljer
Hovedforfatter: Sediri, Hanna
Andre forfattere: Klenk, Hans-Dieter (Prof. Dr.) (BetreuerIn (Doktorarbeit))
Format: Dissertation
Sprog:engelsk
Udgivet: Philipps-Universität Marburg 2015
Fag:
Influenza-A-Viren
Medizin
Influenza-A-Virus
polymerase complex
Grippe
Anpassung
Viren
Adaptation
Säugetiere
mutations
Mutationen
adaptation
Polymerasekomplex
Mutation
Medical sciences Medicine
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Klassifikationsnummer: urn:nbn:de:hebis:04-z2015-02678
Publikationsdatum: 2015-12-08
Datum der Annahme: 2015-04-27
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Lizenz: https://rightsstatements.org/vocab/InC-NC/1.0/
Zugangs-URL: https://archiv.ub.uni-marburg.de/diss/z2015/0267
https://doi.org/10.17192/z2015.0267

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