Investigations into the mechanism of the coenzyme B12 dependent reaction catalyzed by glutamate mutase from Clostridium cochlearium

Investigations into the mechanism of the coenzyme B12 dependent reaction catalyzed by glutamate mutase from Clostridium cochlearium

Aims of this study were the search for inhibitors of the coenzyme B12-dependent glutamate mutase and for insight into the first step of its catalytic mechanism, the homolytic cleavage of the cobalt-carbon bond. Glutamate mutase is composed of two separately isolated protein components S and E2, whic...

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Autore principale: Lyatuu, Fredrick Edwin
Altri autori: Buckel, W. (Prof. Dr.) (Relatore della tesi)
Natura: Dissertation
Lingua:inglese
Pubblicazione: Philipps-Universität Marburg 2012
Soggetti:
Clostridium cochlearium
Biowissenschaften, Biologie
Coenzyme B12
Glutamate Mutase
Coenzym
Methylaspartatmutase
Life sciences
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