Identification and functional characterisation of dL(3)mbt-containing complexes in Drosophila melanogaster

Identification and functional characterisation of dL(3)mbt-containing complexes in Drosophila melanogaster

The Drosophila Lethal (3) malignant brain tumour (dL(3)mbt) protein is the founding member of the family of MBT domain proteins. The MBT domain is a ‘chromatin reader’, a module that specifically recognises mono- and di-methylated lysines within histone tails. In vitro studies suggest that these do...

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Bibliographic Details
Main Author: Meier, Karin
Contributors: Brehm, Alexander (Prof. Dr.) (Thesis advisor)
Format: Doctoral Thesis
Language:English
Published: Philipps-Universität Marburg 2012
Subjects:
Medizin
Multiproteinkomplex
Gene regulation
Repression <Genetik>
Chromatin
Multi-protein complex
Genregulation
Gene repression
Medical sciences Medicine
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