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Interferon regulatory factors 1 and 4 in T cell mediated immune modulation
The transcription factor interferon regulatory factor (IRF) 1 is essential for T helper cell 1 differentiation. Hereby, the respective Irf1 knockout mouse displays a severe immune defect and has an Th2 directed immune status per se. This effect is measurable by increased production of interleukin-4,...
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| 格式: | Dissertation |
| 语言: | 英语 |
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Philipps-Universität Marburg
2011
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| 在线阅读: | PDF-Volltext |
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