Fragment based Drug Discovery; Design and Validation of a Fragment Library; Computer-based Fragment Screening and Fragment-to-Lead Expansion
In recent years, fragment screening has become a popular approach to identify new lead structures. Fragments are usually defined by the Astex ‘rule of three’ (RO3). Surface Plasmon Resonance (SPR), Nuclear Magnetic Resonance spectroscopy (NMR), biochemical assays and X-ray crystallography are effici...
Spremljeno u:
Glavni autor: | |
---|---|
Daljnji autori: | |
Format: | Dissertation |
Jezik: | engleski |
Izdano: |
Philipps-Universität Marburg
2011
|
Teme: | |
Online pristup: | PDF cijeli tekst |
Oznake: |
Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!
|
Budi prvi tko komentira!