Fragment based Drug Discovery; Design and Validation of a Fragment Library; Computer-based Fragment Screening and Fragment-to-Lead Expansion
In recent years, fragment screening has become a popular approach to identify new lead structures. Fragments are usually defined by the Astex ‘rule of three’ (RO3). Surface Plasmon Resonance (SPR), Nuclear Magnetic Resonance spectroscopy (NMR), biochemical assays and X-ray crystallography are effici...
Gespeichert in:
主要作者: | |
---|---|
其他作者: | |
格式: | Dissertation |
语言: | 英语 |
出版: |
Philipps-Universität Marburg
2011
|
主题: | |
在线阅读: | PDF-Volltext |
标签: |
添加标签
没有标签, 成为第一个标记此记录!
|