Fragment based Drug Discovery; Design and Validation of a Fragment Library; Computer-based Fragment Screening and Fragment-to-Lead Expansion
In recent years, fragment screening has become a popular approach to identify new lead structures. Fragments are usually defined by the Astex ‘rule of three’ (RO3). Surface Plasmon Resonance (SPR), Nuclear Magnetic Resonance spectroscopy (NMR), biochemical assays and X-ray crystallography are effici...
Gorde:
Egile nagusia: | |
---|---|
Beste egile batzuk: | |
Formatua: | Dissertation |
Hizkuntza: | ingelesa |
Argitaratua: |
Philipps-Universität Marburg
2011
|
Gaiak: | |
Sarrera elektronikoa: | PDF testu osoa |
Etiketak: |
Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!
|