Fragment based Drug Discovery; Design and Validation of a Fragment Library; Computer-based Fragment Screening and Fragment-to-Lead Expansion
In recent years, fragment screening has become a popular approach to identify new lead structures. Fragments are usually defined by the Astex ‘rule of three’ (RO3). Surface Plasmon Resonance (SPR), Nuclear Magnetic Resonance spectroscopy (NMR), biochemical assays and X-ray crystallography are effici...
Kaydedildi:
Yazar: | |
---|---|
Diğer Yazarlar: | |
Materyal Türü: | Dissertation |
Dil: | İngilizce |
Baskı/Yayın Bilgisi: |
Philipps-Universität Marburg
2011
|
Konular: | |
Online Erişim: | PDF Tam Metin |
Etiketler: |
Etiketle
Etiket eklenmemiş, İlk siz ekleyin!
|
No references were found for this record.