Fragment based Drug Discovery; Design and Validation of a Fragment Library; Computer-based Fragment Screening and Fragment-to-Lead Expansion

Fragment based Drug Discovery; Design and Validation of a Fragment Library; Computer-based Fragment Screening and Fragment-to-Lead Expansion

In recent years, fragment screening has become a popular approach to identify new lead structures. Fragments are usually defined by the Astex ‘rule of three’ (RO3). Surface Plasmon Resonance (SPR), Nuclear Magnetic Resonance spectroscopy (NMR), biochemical assays and X-ray crystallography are effici...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteur: Craan, Tobias Friedrich
Andere auteurs: Klebe, Gerhard (Prof. Dr.) (Thesis begeleider)
Formaat: Dissertation
Taal:Engels
Gepubliceerd in: Philipps-Universität Marburg 2011
Onderwerpen:
FBLD
Fragment
Naturwissenschaften
Fragmentbasierte Leitstrukturentwicklung
Fragmentbibliotek
Fragment library
Natural sciences & mathematics
Online toegang:PDF Full text
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!
No references were found for this record.

Gelijkaardige items