Analysis of a capsid-modified and conditionally replicating, oncolytic adenoviral vector as a novel treatment for human glioblastoma multiforme.

Analysis of a capsid-modified and conditionally replicating, oncolytic adenoviral vector as a novel treatment for human glioblastoma multiforme.

Glioblastoma multiforme (GBM) is the most aggressive brain tumor, and patients rarely survive for more than 2 years. Gene therapy may offer new treatment options and improve the prognosis for patients with GBM. Adenovirus-mediated gene therapy strategies for brain tumors have been limited by ineffic...

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Dettagli Bibliografici
Autore principale: Wohlfahrt, Martin E.
Altri autori: Lingelbach, Klaus (Prof.) (Relatore della tesi)
Natura: Dissertation
Lingua:inglese
Pubblicazione: Philipps-Universität Marburg 2010
Soggetti:
TRAIL
Glioblastoma multiforme, TRAIL
Oncolysis
Adenovirus
Onkolyse
Glioblastom
Adenovirus 5
Naturwissenschaften
Natural sciences & mathematics
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