Analysis of a capsid-modified and conditionally replicating, oncolytic adenoviral vector as a novel treatment for human glioblastoma multiforme.

Glioblastoma multiforme (GBM) is the most aggressive brain tumor, and patients rarely survive for more than 2 years. Gene therapy may offer new treatment options and improve the prognosis for patients with GBM. Adenovirus-mediated gene therapy strategies for brain tumors have been limited by ineffic...

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Príomhchruthaitheoir: Wohlfahrt, Martin E.
Rannpháirtithe: Lingelbach, Klaus (Prof.) (Comhairleoir tráchtais)
Formáid: Dissertation
Teanga:Béarla
Foilsithe / Cruthaithe: Philipps-Universität Marburg 2010
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Gairmuimhir: urn:nbn:de:hebis:04-z2010-06444
Dáta a fhoilsithe: 2010-12-02
Foinse: A capsid-modified, conditionally replicating oncolytic adenovirus vector expressing TRAIL Leads to enhanced cancer cell killing in human glioblastoma models. Cancer Res. 2007 Sep 15;67(18):8783-90. PMID: 17875719
Datum der Annahme: 2010-07-08
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Lizenz: https://rightsstatements.org/vocab/InC-NC/1.0/
URL Rochtana: https://archiv.ub.uni-marburg.de/diss/z2010/0644
https://doi.org/10.17192/z2010.0644