Chemoenzymatic Synthesis of Chromodepsipeptides and Natural Product Discovery via Genome Mining

Chemoenzymatic Synthesis of Chromodepsipeptides and Natural Product Discovery via Genome Mining

Recent advances in the development of sequencing technologies have enabled the identification of a multitude of bacterial gene clusters, putatively involved in the biosynthesis of nonribosomal peptides (NRPs). Peptides of nonribosomal origin constitute a class of structurally and functionally divers...

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Bibliographic Details
Main Author: Robbel, Lars
Contributors: Marahiel, Mohamed (Prof. Dr.) (Thesis advisor)
Format: Doctoral Thesis
Language:German
Published: Philipps-Universität Marburg 2010
Subjects:
Acetylierung
cyclodimerization
Thioesterase II
Chemie
Modifikation <Biochemie>
Hydroxylierung
Zyklodimerisierung
Sekundärmetabolit
Genanalyse
NRPS
acetylation
Genomische Mining
genome mining
hydroxylation
Chemistry & allied sciences
Online Access:PDF Full Text
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